Evidence map›Paper›PMID 33947364›Full record

ArticleBMC psychiatry2021

Decision making under ambiguity and risk in adolescent-onset schizophrenia.

Dandan Li, Fengyan Zhang, Lu Wang, Yifan Zhang, Tingting Yang, Kai Wang, Chunyan Zhu

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Dandan Li *Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
Fengyan Zhang *Children's Rehabilitation Department, Wuhan Mental Health Center, Wuhan, 430012, China.
Lu WangDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
Yifan ZhangSchool of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230022, China.
Tingting YangSchool of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230022, China.
Kai WangDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China. wangkai1964@126.com.
Chunyan ZhuAnhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China. ayswallow@126.com.
Anhui Medical University · CNAnhui Mental Health Center · CNFirst Affiliated Hospital of Anhui Medical University · CNWuhan Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNumerous studies have identified impaired decision making (DM) under both ambiguity and risk in adult patients with schizophrenia. However, the assessment of DM in patients with adolescent-onset schizophrenia (AOS) has been challenging as a result of the instability and heterogeneity of manifestations. The Iowa Gambling Task (IGT) and Game of Dice Task (GDT), which are frequently used to evaluate DM respectively under ambiguity and risk, are sensitive to adolescents and neuropsychiatric patients. Our research intended to examine the performance of DM in a relatively large sample of patients with AOS using the above-mentioned two tasks. We also aimed to take a closer look at the relationship between DM and symptom severity of schizophrenia.

methodsWe compared the performance of DM in 71 patients with AOS and 53 well-matched healthy controls using IGT for DM under ambiguity and GDT for DM under risk through net scores, total scores and feedback ration. Neuropsychological tests were conducted in all participants. Clinical symptoms were evaluated by using Positive and Negative Syndrome Scale (PANSS) in 71 patients with AOS. Pearson's correlation revealed the relationship among total score of DM and clinical and neuropsychological data.

resultsCompared to healthy controls, patients with AOS failed to show learning effect and had a significant difference on the 5th block in IGT and conducted more disadvantageous choices as well as exhibited worse negative feedback rate in GDT. Apart from DM impairment under risk, diminished DM abilities under ambiguity were found related to poor executive function in AOS in the present study.

conclusionsOur findings unveiled the abnormal pattern of DM in AOS, mainly reflected under the risky condition, extending the knowledge on the performance of DM under ambiguity and risk in AOS. Inefficient DM under risk may account for the lagging impulse control and the combined effects of developmental disease. In addition, our study demonstrated that the performance on IGT was related to executive function in AOS.

Indexed as

GamblingSchizophreniaAdolescentAdultDecision MakingHumansNeuropsychological TestsRisk-TakingAdolescent-onset schizophreniaDecision makingGame of dice taskIowa gambling task

Identifiers

PMID33947364
PMCPMC8094464
OpenAlexW3158402093

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.