ArticleBMC psychiatry2021
The Eating Disorders Genetics Initiative (EDGI): study protocol.
Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04378101 (Eating Disorders Genetics Initiative), which is not on this map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Eating Disorders Genetics Initiative (EDGI)
Who cites it
36 citing papers in PubMed, 73 citations in OpenAlex.
- Associations between compulsive exercise and mental health constructs in eating disorders.Journal of eating disorders · 2026Article
- Maladaptive Exercise in People With a Lifetime History of Eating Disorders: A Multicountry Observational Study.The International journal of eating disorders · 2026Observational
- Hoarding Symptoms in Eating Disorders: An Observational Cross-Sectional Study.The International journal of eating disorders · 2025Observational
- A case-control study of potentially traumatic events in Mexican individuals with eating disorders.Eating disorders · 2025Article
- Beyond the Diagnostic Checklist: A Large-Scale Analysis of Under-Recognized Weight Loss Behaviors in Individuals With Eating Disorders.The International journal of eating disorders · 2025Article
- Descriptives and Genetic Correlates of Eating Disorder Diagnostic Transitions and Presumed Remission in the Danish Registry.Biological psychiatry · 2025Article
- Personalised and precision mental health in eating disorders: why routine outcome measurement is key.Journal of eating disorders · 2025Review
- The Eating Disorders Genetics Initiative 2 (EDGI2): study protocol.BMC psychiatry · 2025Article
- Psychiatric genetics in the diverse landscape of Latin American populations.Nature genetics · 2025Review
- The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder.Molecular psychiatry · 2025Article
- Article
- Obsessive-compulsive symptoms in individuals with a history of eating disorders.Journal of affective disorders · 2025Observational
- Harnessing precision nutrition to individualize weight restoration in anorexia nervosa.Journal of eating disorders · 2025Review
- Article
- Eating behaviour and eating disorders in individuals with rare neurodevelopmental variants: current knowledge and future research directions.Frontiers in psychiatry · 2025Article
- Assessing Avoidant/Restrictive Food Intake Disorder (ARFID) Symptoms Using the Nine Item ARFID Screen in >9000 Swedish Adults With and Without Eating Disorders.The International journal of eating disorders · 2024Article
- Descriptives and genetic correlates of eating disorder diagnostic transitions and presumed remission in the Danish registry.medRxiv : the preprint server for health sciences · 2024Article
- Polygenic Risk of Mental Disorders and Subject-Specific School Grades.Biological psychiatry · 2024Article
- Relationship of Genetic Polymorphisms and Microbial Composition with Binge Eating Disorder: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder.Research square · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 4 institutions in 5 countries.
Funding
Abstract
backgroundThe Eating Disorders Genetics Initiative (EDGI) is an international investigation exploring the role of genes and environment in anorexia nervosa, bulimia nervosa, and binge-eating disorder.
methodsA total of 14,500 individuals with eating disorders and 1500 controls will be included from the United States (US), Australia (AU), New Zealand (NZ), and Denmark (DK). In the US, AU, and NZ, participants will complete comprehensive online phenotyping and will submit a saliva sample for genotyping. In DK, individuals with eating disorders will be identified by the National Patient Register, and genotyping will occur using bloodspots archived from birth. A genome-wide association study will be conducted within EDGI and via meta-analysis with other data from the Eating Disorders Working Group of the Psychiatric Genomics Consortium (PGC-ED). DISCUSSION: EDGI represents the largest genetic study of eating disorders ever to be conducted and is designed to rapidly advance the study of the genetics of the three major eating disorders (anorexia nervosa, bulimia nervosa, and binge-eating disorder). We will explicate the genetic architecture of eating disorders relative to each other and to other psychiatric and metabolic disorders and traits. Our goal is for EDGI to deliver "actionable" findings that can be transformed into clinically meaningful insights.
trial registrationEDGI is a registered clinical trial: clinicaltrials.gov NCT04378101 .
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.