Evidence map›Paper›PMID 33947040›Full record

ArticleTropical medicine and infectious disease2021

Prevalence and Risk Factors for Lymphocytic Choriomeningitis Virus Infection in Continental Croatian Regions.

Tatjana Vilibic-Cavlek, Tena Oreski, Misa Korva, Branko Kolaric, Vladimir Stevanovic, Snjezana Zidovec-Lepej, Irena Tabain, Pavle Jelicic, Bozana Miklausic-Pavic, Vladimir Savic and 2 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Nociceptor neurons shape antiviral immunity.Journal of neuroinflammation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Tatjana Vilibic-CavlekDepartment of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia.ORCID 0000-0002-1877-5547
Tena OreskiGensynthese, Eurofins Genomics, 85560 Ebersberg, Germany.
Misa KorvaFaculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-1501-1004
Branko KolaricDepartment of Public Health Gerontology, Andrija Stampar Teaching Institute of Public Health, 10000 Zagreb, Croatia.
Vladimir StevanovicDepartment of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Snjezana Zidovec-LepejDepartment of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases "Dr Fran Mihaljevic", 10000 Zagreb, Croatia.ORCID 0000-0001-9852-5806
Irena TabainDepartment of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia.
Pavle JelicicEnvironmental Health Department, Croatian Institute of Public Health, 10000 Zagreb, Croatia.
Bozana Miklausic-PavicDepartment for General Infectious Diseases with Day Hospital, University Hospital for Infectious Diseases "Dr Fran Mihaljevic", 10000 Zagreb, Croatia.
Vladimir SavicPoultry Center, Croatian Veterinary Institute, 10000 Zagreb, Croatia.ORCID 0000-0003-0398-5346
Ljubo BarbicDepartment of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Tatjana Avsic-ZupancFaculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-6243-0688
University of Zagreb · HRHrvatski zavod za javno zdravstvo · HRUniversity Hospital for Infectious Diseases "Dr Fran Mihaljevic" · HRUniversity of Ljubljana · SICroatian Veterinary Institute · HREurofins (Germany) · DEUniversity of Rijeka · HR

Funding

University of Zagreb School of Medicine Prevalence of lymphocytic choriomeningitis in the Croatian mainland
6 · The paper itself

Abstract

Lymphocytic choriomeningitis virus (LCMV) is a neglected human pathogen associated with aseptic meningitis, severe systemic infections in immunocompromised persons, and congenital anomalies. Data on the prevalence of LCMV infections are scarce. We analyzed the seroprevalence of LCMV in continental Croatian regions. A total of 338 serum samples of professionally exposed (forestry workers, hunters, agriculture workers in contact with rodents) and non-exposed populations (general population, pregnant women) were tested for the presence of LCMV antibodies using indirect immunofluorescence assay. No participants reported recent febrile disease. LCMV IgG antibodies were detected in 23/6.8% of participants: 9.8% exposed persons and 5.1% non-exposed persons (6.1% in the general population and 3.9% in pregnant women). No participants were LCMV IgM positive. Although higher seropositivity was found in males compared to females (8.9% vs. 4.7%), inhabitants of suburban/rural areas compared to inhabitants of urban areas (9.2% vs. 4.6%), and persons who used well as a source of water compared to those who used tap (11.4% vs. 5.6%), these differences did not reach statistical significance. Results of logistic regression showed that the presence of rodents in the house/yard and cleaning rodent nests were associated with an elevated risk for LCMV infection (OR = 2.962, 95% CI = 1.019-8.607).

Indexed as

Croatiageneral populationlymphocytic choriomeningitis viruspregnant womenprofessionally exposedseroprevalence

Identifiers

PMID33947040
PMCPMC8167717
OpenAlexW3159482007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.