Evidence map›Paper›PMID 33947014›Full record

ArticleViruses2021

Fast Detection of SARS-CoV-2 RNA Directly from Respiratory Samples Using a Loop-Mediated Isothermal Amplification (LAMP) Test.

Olympia E Anastasiou, Caroline Holtkamp, Miriam Schäfer, Frieda Schön, Anna Maria Eis-Hübinger, Andi Krumbholz

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

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  12. Performance of the LIAISONPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Olympia E AnastasiouInstitute for Virology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0003-2178-3182
Caroline HoltkampInstitute for Virology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Miriam SchäferLabor Dr. Krause und Kollegen MVZ GmbH, 24106 Kiel, Germany.
Frieda SchönLabor Dr. Krause und Kollegen MVZ GmbH, 24106 Kiel, Germany.
Anna Maria Eis-HübingerInstitute of Virology, Medical Faculty, University Hospital Bonn, 53127 Bonn, Germany.
Andi KrumbholzLabor Dr. Krause und Kollegen MVZ GmbH, 24106 Kiel, Germany.
University of Duisburg-Essen · DEChristian-Albrechts-Universität zu Kiel · DEUniversity Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The availability of simple SARS-CoV-2 detection methods is crucial to contain the COVID-19 pandemic. This study examined whether a commercial LAMP assay can reliably detect SARS-CoV-2 genomes directly in respiratory samples without having to extract nucleic acids (NA) beforehand. Nasopharyngeal swabs (NPS,

Indexed as

COVID-19COVID-19 Nucleic Acid TestingDNA, ViralHumansMolecular Diagnostic TechniquesNasopharynxNucleic Acid Amplification TechniquesSARS-CoV-2Sensitivity and SpecificitySpecimen HandlingDNA, ViralCOVID-19direct testingLAMPloop-mediated isothermal amplificationnucleic acidsRT-PCRSARS-CoV-2

Identifiers

PMID33947014
PMCPMC8146783
OpenAlexW3143862833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.