ArticleDiagnostics (Basel, Switzerland)2021
Evaluating Retinal and Choroidal Perfusion Changes after Isometric and Dynamic Activity Using Optical Coherence Tomography Angiography.
Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Choriocapillaris Perfusion after 8 Weeks of High-Speed Circuit Training in Older Healthy Adults.Current eye research · 2024Trial
- Decreased retinal capillary density as a beneficial response to 24-week high-speed circuit resistant training in healthy older adults.Microvascular research · 2024Trial
- Choriocapillaris Flow-Enriched Prediction of Retinal Sensitivity Using OCT-Derived Biomarkers in Intermediate Age-Related Macular Degeneration.Journal of clinical medicine · 2026Article
- Acute effects of high-intensity interval training on retinal microvascular circulation in cancer patients and healthy controls: insight from the optical coherence tomography angiography.European journal of applied physiology · 2026Article
- Association Between Intraocular Pressure Changes and Optic Nerve Head and Macular Perfusion Parameters During Isometric Exercise: OCTA Study.Diagnostics (Basel, Switzerland) · 2026Article
- Localising OCTA changes induced by the isometric hand-grip test to the superficial retina in neovascular age-related macular degeneration.Eye and vision (London, England) · 2025Article
- Retinal vascular reactivity in carriers of X-linked inherited retinal disease - a study using optical coherence tomography angiography.Frontiers in ophthalmology · 2024Article
- Relationship of Vessel Density to Vessel Length Density in Patients with Treated Fabry Disease.Diagnostics (Basel, Switzerland) · 2023Article
- Review
- Analysis of the Peripapillary and Macular Regions Using OCT Angiography in Patients with Schizophrenia and Bipolar Disorder.Journal of clinical medicine · 2021Article
- Association of Microvasculature and Macular Sensitivity in Idiopathic Macular Epiretinal Membrane: Using OCT Angiography and Microperimetry.Frontiers in medicine · 2021Article
- Optical coherence tomography angiography in cardiovascular disease.Progress in cardiovascular diseasesReview
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optical coherence tomography angiography (OCTA) is a non-invasive tool for imaging and quantifying the retinal and choroidal perfusion state in vivo. This study aimed to evaluate the acute effects of isometric and dynamic exercise on retinal and choroidal sublayer perfusion using OCTA. A pilot study was conducted on young, healthy participants, each of whom performed a specific isometric exercise on the first day and a dynamic exercise the day after. At baseline and immediately after the exercise, heart rate (HR), mean arterial pressure (MAP), superficial capillary plexus perfusion (SCPP), deep capillary plexus perfusion (DCPP), choriocapillaris perfusion (CCP), Sattlers's layer perfusion (SLP), and Haller's layer perfusion (HLP) were recorded. A total of 34 eyes of 34 subjects with a mean age of 32.35 ± 7.87 years were included. HR as well as MAP increased significantly after both types of exercise. Both SCPP and DCPP did not show any significant alteration due to isometric or dynamic exercise. After performing dynamic exercise, CCP, SLP, as well as HLP significantly increased. Changes in MAP correlated significantly with changes in HLP after the dynamic activity. OCTA-based analysis in healthy adults following physical activity demonstrated a constant retinal perfusion, supporting the theory of autoregulatory mechanisms. Dynamic exercise, as opposed to isometric activity, significantly changed choroidal perfusion. OCTA imaging may represent a novel and sensitive tool to expand the diagnostic spectrum in the field of sports medicine.
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