Evidence map›Paper›PMID 33946956›Full record

ReviewGenes2021

Cryptochromes and the Circadian Clock: The Story of a Very Complex Relationship in a Spinning World.

Loredana Lopez, Carlo Fasano, Giorgio Perrella, Paolo Facella

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Photo-CIDNP of Solvent-Exposed Flavins in Flavoproteins.The journal of physical chemistry letters · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Room-temperature serial synchrotron crystallography of Drosophila cryptochrome.Acta crystallographica. Section D, Structural biology · 2022
    Article
  19. Signaling Mechanisms by Arabidopsis Cryptochromes.Frontiers in plant science · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Loredana LopezItalian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), TERIN-BBC-BBE, Trisaia Research Center, 75026 Rotondella, Matera, Italy.
Carlo FasanoItalian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), TERIN-BBC-BBE, Trisaia Research Center, 75026 Rotondella, Matera, Italy.ORCID 0000-0002-6368-1398
Giorgio PerrellaItalian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), TERIN-BBC-BBE, Trisaia Research Center, 75026 Rotondella, Matera, Italy.ORCID 0000-0001-8972-1733
Paolo FacellaItalian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), TERIN-BBC-BBE, Trisaia Research Center, 75026 Rotondella, Matera, Italy.
National Agency for New Technologies, Energy and Sustainable Economic Development · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptochromes are flavin-containing blue light photoreceptors, present in most kingdoms, including archaea, bacteria, plants, animals and fungi. They are structurally similar to photolyases, a class of flavoproteins involved in light-dependent repair of UV-damaged DNA. Cryptochromes were first discovered in

Indexed as

Circadian ClocksCryptochromesEpigenesis, GeneticPlant ProteinsPlantsCryptochromesPlant ProteinsArabidopsiscell cyclechromatincircadian clockcryptochromesepigeneticgene expression regulationlight

Identifiers

PMID33946956
PMCPMC8145066
OpenAlexW3158613939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.