Evidence map›Paper›PMID 33946947›Full record

ArticleInternational journal of molecular sciences2021

Exploring the Ion Channel TRPV2 and Testicular Macrophages in Mouse Testis.

Katja Eubler, Pia Rantakari, Heidi Gerke, Carola Herrmann, Annika Missel, Nina Schmid, Lena Walenta, Shibojyoti Lahiri, Axel Imhof, Leena Strauss and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Identification of Catecholamine and Drug Target αJournal of clinical medicine · 2024
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Katja EublerCell Biology-Anatomy III, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.
Pia RantakariTurku Bioscience Center, University of Turku and Åbo Akademi University, FI-20300 Turku, Finland.
Heidi GerkeTurku Bioscience Center, University of Turku and Åbo Akademi University, FI-20300 Turku, Finland.
Carola HerrmannCell Biology-Anatomy III, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.
Annika MisselCell Biology-Anatomy III, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.
Nina SchmidCell Biology-Anatomy III, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.
Lena WalentaCell Biology-Anatomy III, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.
Shibojyoti LahiriProtein Analysis Unit, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.ORCID 0000-0002-2018-9870
Axel ImhofProtein Analysis Unit, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.
Leena StraussResearch Center for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, FI-20300 Turku, Finland.
Matti PoutanenResearch Center for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, FI-20300 Turku, Finland.
Artur MayerhoferCell Biology-Anatomy III, Biomedical Center Munich (BMC), Faculty of Medicine, Ludwig-Maximilian-University (LMU), D-82152 Planegg-Martinsried, Germany.ORCID 0000-0002-9388-4639
Ludwig-Maximilians-Universität München · DEÅbo Akademi University · FIUniversity of Turku · FI

Funding

Deutsche Forschungsgemeinschaft MA1080/27-1 and 31-1 (project number 456828204) and SFB1123 TP Z02
6 · The paper itself

Abstract

The cation channel TRPV2 is known to be expressed by murine macrophages and is crucially involved in their functionality. Macrophages are frequent cells of the mouse testis, an immune-privileged and steroid-producing organ. TRPV2 expression by testicular macrophages and possible changes associated with age or inflammation have not been investigated yet. Therefore, we studied testes of young adult and old wild-type (WT) and AROM

Indexed as

Adrenal GlandsAge FactorsAnimalsAromataseBrainCalcium ChannelsDisease Models, AnimalGenotypeInfertility, MaleLectins, C-TypeMacrophagesMaleMannose-Binding LectinsMannose ReceptorMiceMice, TransgenicAromataseCalcium ChannelsCybb protein, mouseCYP19A1 protein, humanLectins, C-TypeMannose-Binding LectinsMannose ReceptorNADPH Oxidase 2Receptors, Cell SurfaceRNA, MessengerTrpv2 protein, mouseTRPV Cation ChannelsTumor Necrosis Factor-alphaagingAROM+infertilityinflammationmacrophagestestisTRPV2

Identifiers

PMID33946947
PMCPMC8124949
OpenAlexW3159243604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.