Evidence map›Paper›PMID 33946919›Full record

ArticleCells2021

Oral Administration of

JooYeon Jhun, Keun-Hyung Cho, Dong-Hwan Lee, Ji Ye Kwon, Jin Seok Woo, Jiyoung Kim, Hyun Sik Na, Sung-Hwan Park, Seok Jung Kim, Mi-La Cho

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 4 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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  4. Enterochromaffin Cells: Sentinels to Gut Microbiota in Hyperalgesia?Frontiers in cellular and infection microbiology · 2021
    Pooled it
  5. mSystems · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

JooYeon JhunRheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul 06591, Korea.
Keun-Hyung ChoRheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul 06591, Korea.
Dong-Hwan LeeDepartment of Orthopedic Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-7798-5894
Ji Ye KwonRheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul 06591, Korea.
Jin Seok WooRheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0001-8921-2832
Jiyoung KimRheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul 06591, Korea.
Hyun Sik NaRheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul 06591, Korea.
Sung-Hwan ParkDivision of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul 06591, Korea.
Seok Jung KimDepartment of Orthopedic Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-9116-8786
Mi-La ChoRheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul 06591, Korea.
Catholic University of Korea · KRThe Catholic University of Korea Uijeongbu St. Mary's Hospital · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea HI20C1496the National Research Foundation of Korea(NRF) funded by the Ministry of Education 2020R1I1A1A01072520the National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIT) NRF-2018R1C1B6005854
6 · The paper itself

Abstract

Osteoarthritis (OA) is the most common form of arthritis and age-related degenerative joint disorder, which adversely affects quality of life and causes disability. However, the pathogenesis of OA remains unclear. This study was performed to examine the effects of

Indexed as

ProbioticsAnimalsBiological TherapyCells, CulturedChemokine CCL2ChondrocytesCollagenGanglia, SpinalHumansInterleukin-1betaJointsLacticaseibacillus rhamnosusOsteoarthritisPain ManagementPPAR gammaRatsCcl2 protein, ratCcr2 protein, ratChemokine CCL2CollagenInterleukin-1betaPPAR gammaReceptors, CCR2SOX9 Transcription FactorTissue Inhibitor of Metalloproteinase-1Tissue Inhibitor of Metalloproteinase-3inflammationLactobacillus rhamnosusmicrobiotamonosodium iodoacetate (MIA)osteoarthritis

Identifiers

PMID33946919
PMCPMC8146916
OpenAlexW3135301143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.