ArticleMolecules (Basel, Switzerland)2021
Identification of New Potential Inhibitors of Quorum Sensing through a Specialized Multi-Level Computational Approach.
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Integrated in Vitro and in Silico Investigation of Antimicrobial, Anti-biofilm, and Quorum-Sensing Inhibitory Activities of Allium atroviolaceum Bulb Extract.Applied biochemistry and biotechnology · 2026Article
- Integrative In vitro and In Silico analysis of marine Actinobacterium,Toxicology research · 2025Article
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- Computational tools for exploring peptide-membrane interactions in gram-positive bacteria.Computational and structural biotechnology journal · 2023Review
- Liposomal Formulations Loaded with a Eugenol Derivative for Application as Insecticides: Encapsulation Studies and In Silico Identification of Protein Targets.Nanomaterials (Basel, Switzerland) · 2022Article
- Quorum Sensing and Biofilm Disrupting Potential of Imidazole Derivatives in Chromobacterium violaceum Using Antimicrobial and Drug Discovery Approaches.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Development of Neuropeptide Y and Cell-Penetrating Peptide MAP Adsorbed onto Lipid Nanoparticle Surface.Molecules (Basel, Switzerland) · 2022Article
- Drug Repurposing TargetingAntibiotics (Basel, Switzerland) · 2022Article
- RepurposingAntibiotics (Basel, Switzerland) · 2022Article
- Computational and Biological Evaluation ofPharmaceuticals (Basel, Switzerland) · 2022Article
- The role of eugenol and ferulic acid as the competitive inhibitors of transcriptional regulator RhlR inMethodsX · 2022Article
- Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights.Molecules (Basel, Switzerland) · 2021Article
- New carvacrol and thymol derivatives as potential insecticides: synthesis, biological activity, computational studies and nanoencapsulation.RSC advances · 2021Article
- In Silico Identification of Possible Inhibitors for Protein Kinase B (PknB) ofMolecules (Basel, Switzerland) · 2021Article
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3 authors.
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Abstract
Biofilms are aggregates of microorganisms anchored to a surface and embedded in a self-produced matrix of extracellular polymeric substances and have been associated with 80% of all bacterial infections in humans. Because bacteria in biofilms are less amenable to antibiotic treatment, biofilms have been associated with developing antibiotic resistance, a problem that urges developing new therapeutic options and approaches. Interfering with quorum-sensing (QS), an important process of cell-to-cell communication by bacteria in biofilms is a promising strategy to inhibit biofilm formation and development. Here we describe and apply an in silico computational protocol for identifying novel potential inhibitors of quorum-sensing, using CviR-the quorum-sensing receptor from
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