Evidence map›Paper›PMID 33946906›Full record

ArticleJournal of clinical medicine2021

Possible Earlier Diagnosis of Ulcerative Colitis-Associated Neoplasia: A Retrospective Analysis of Interval Cases during Surveillance.

Takashi Hisabe, Toshiyuki Matsui, Kazutomo Yamasaki, Tsuyoshi Morokuma, Kenmei Aomi, Naoyuki Yoshizawa, Noritaka Takatsu, Kenshi Yao, Toshiharu Ueki, Kitaro Futami and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Takashi HisabeDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.ORCID 0000-0001-7308-1030
Toshiyuki MatsuiDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Kazutomo YamasakiDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Tsuyoshi MorokumaDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Kenmei AomiDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Naoyuki YoshizawaDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Noritaka TakatsuDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.ORCID 0000-0002-1967-5169
Kenshi YaoDepartment of Endoscopy, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.ORCID 0000-0003-0863-3649
Toshiharu UekiDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Kitaro FutamiDepartment of Surgery, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Hiroshi TanabeDepartment of Pathology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Akinori IwashitaDepartment of Pathology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka 818-8502, Japan.
Fukuoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly detection of ulcerative colitis-associated neoplasia (UCAN) is often difficult. The aim of this study was to clarify the morphology of initial UCAN.

methodsWhite-light colonoscopy images obtained within the 2 years before UCAN diagnosis were retrospectively reviewed. The primary endpoint was the frequency of visible or invisible neoplasia on the endoscopic images before UCAN diagnosis. The secondary endpoints were comparisons of (1) visible or invisible neoplasia on initial endoscopic images of early-stage and advanced cancers, (2) the clinical backgrounds of patients in whom neoplasia was visible or invisible on initial endoscopic images, and (3) the clinical backgrounds of patients with distinct and indistinct UCAN borders.

resultsOf the 27 UCAN lesions (11 early-stage; 16 advanced-stage), 25.9% (

conclusionMore careful surveillance is needed because rectum lesions and inflammation are difficult to identify as neoplasia even within the 2 years before a UCAN diagnosis.

Indexed as

colorectal cancerinterval cancersurveillanceulcerative colitisulcerative colitis-associated neoplasia

Identifiers

PMID33946906
PMCPMC8124807
OpenAlexW3158206019

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.