Evidence map›Paper›PMID 33946902›Full record

ArticleInternational journal of molecular sciences2021

Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells.

Kosuke Sako, Daisuke Sakai, Yoshihiko Nakamura, Jordy Schol, Erika Matsushita, Takayuki Warita, Natsumi Horikita, Masato Sato, Masahiko Watanabe

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

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  15. JOR spine · 2022
    Article
  16. Review
  17. Review
  18. Concepts of Regeneration for Spinal Diseases in 2021.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kosuke SakoDepartment of Orthopedic Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.ORCID 0000-0002-4305-7774
Daisuke SakaiDepartment of Orthopedic Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.ORCID 0000-0003-4189-9270
Yoshihiko NakamuraResearch Center for Regenerative Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
Jordy ScholResearch Center for Regenerative Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.ORCID 0000-0001-5489-2591
Erika MatsushitaResearch Center for Regenerative Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
Takayuki WaritaResearch Center for Regenerative Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
Natsumi HorikitaResearch Center for Regenerative Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
Masato SatoDepartment of Orthopedic Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.ORCID 0000-0003-4049-7325
Masahiko WatanabeDepartment of Orthopedic Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.ORCID 0000-0001-9038-0446
Tokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous work showed a link between Tie2

Indexed as

AdolescentAdultCells, CulturedCollagen Type IIFemaleFibroblast Growth Factor 1Fibroblast Growth Factor 2FlavonoidsHumansIntervertebral Disc DisplacementMaleMAP Kinase Signaling SystemNucleus PulposusPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptor, TIE-22-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-oneAKT1 protein, humanCOL2A1 protein, humanCollagen Type IIFibroblast Growth Factor 1Fibroblast Growth Factor 2FlavonoidsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptor, TIE-2Recombinant Fusion ProteinsTEK protein, humanAktbasic fibroblast growth factorchimera fibroblast growth factorERKintervertebral discnucleus pulposusnucleus pulposus progenitor cellTie2 receptortype II collagenwhole tissue culture

Identifiers

PMID33946902
PMCPMC8124367
OpenAlexW3158147923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.