Evidence map›Paper›PMID 33946892›Full record

ReviewNutrients2021

Development of Personalized Nutrition: Applications in Lactose Intolerance Diagnosis and Management.

Millie Porzi, Kathryn J Burton-Pimentel, Barbara Walther, Guy Vergères

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Millie PorziLaboratory of Human Nutrition, Department of Health Sciences and Technology, ETH Zurich, 8092 Zurich, Switzerland.
Kathryn J Burton-PimentelAgroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Bern, Switzerland.
Barbara WaltherAgroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Bern, Switzerland.
Guy VergèresAgroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Bern, Switzerland.
Agroscope · CHETH Zurich · CHFederal Department of Economic Affairs, Education and Research · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent discoveries in the "omics" field and the growing focus on preventive health have opened new avenues for personalized nutrition (PN), which is becoming an important theme in the strategic plans of organizations that are active in healthcare, food, and nutrition research. PN holds great potential for individual health optimization, disease management, public health interventions, and product innovation. However, there are still multiple challenges to overcome before PN can be truly embraced by the public and healthcare stakeholders. The diagnosis and management of lactose intolerance (LI), a common condition with a strong inter-individual component, is explored as an interesting example for the potential role of these technologies and the challenges of PN. From the development of genetic and metabolomic LI diagnostic tests that can be carried out in the home, to advances in the understanding of LI pathology and individualized treatment optimization, PN in LI care has shown substantial progress. However, there are still many research gaps to address, including the understanding of epigenetic regulation of lactase expression and how lactose is metabolized by the gut microbiota, in order to achieve better LI detection and effective therapeutic interventions to reverse the potential health consequences of LI.

Indexed as

Nutritional SciencesPrecision MedicineEpigenesis, GeneticHumansLactaseLactoseLactose IntoleranceLactaseLactosedairy productsepigeneticsfunctional foodsgenetic testinggut microbiotalactase persistencelactose intoleranceomicspersonalized nutritionpolymorphism

Identifiers

PMID33946892
PMCPMC8145768
OpenAlexW3158978219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.