Evidence map›Paper›PMID 33946790›Full record

ReviewInternational journal of molecular sciences2021

Recent Advances in Effector-Triggered Immunity in Plants: New Pieces in the Puzzle Create a Different Paradigm.

Quang-Minh Nguyen, Arya Bagus Boedi Iswanto, Geon Hui Son, Sang Hee Kim

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. StablePlants (Basel, Switzerland) · 2026
    Article
  6. Beyond Resistance Genes: Silencing Susceptibility.International journal of molecular sciences · 2026
    Review
  7. Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  8. Review
  9. Review
  10. A century ofPlant signaling & behavior · 2025
    Review
  11. Article
  12. Expression characteristics ofPlant signaling & behavior · 2025
    Article
  13. Expression characteristics ofPlant signaling & behavior · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Reinforced Defenses:International journal of molecular sciences · 2025
    Review
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Quang-Minh NguyenDivision of Applied Life Science (BK21 Four Program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea.ORCID 0000-0003-1281-8961
Arya Bagus Boedi IswantoDivision of Applied Life Science (BK21 Four Program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea.ORCID 0000-0002-8158-4698
Geon Hui SonDivision of Applied Life Science (BK21 Four Program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea.
Sang Hee KimDivision of Applied Life Science (BK21 Four Program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea.ORCID 0000-0003-1831-4633

Funding

BioGreen21 Agri-Tech Innovation Program, Rural Development Administration, Republic of Korea Project No. PJ015756
6 · The paper itself

Abstract

Plants rely on multiple immune systems to protect themselves from pathogens. When pattern-triggered immunity (PTI)-the first layer of the immune response-is no longer effective as a result of pathogenic effectors, effector-triggered immunity (ETI) often provides resistance. In ETI, host plants directly or indirectly perceive pathogen effectors via resistance proteins and launch a more robust and rapid defense response. Resistance proteins are typically found in the form of nucleotide-binding and leucine-rich-repeat-containing receptors (NLRs). Upon effector recognition, an NLR undergoes structural change and associates with other NLRs. The dimerization or oligomerization of NLRs signals to downstream components, activates "helper" NLRs, and culminates in the ETI response. Originally, PTI was thought to contribute little to ETI. However, most recent studies revealed crosstalk and cooperation between ETI and PTI. Here, we summarize recent advancements in our understanding of the ETI response and its components, as well as how these components cooperate in the innate immune signaling pathways. Based on up-to-date accumulated knowledge, this review provides our current perspective of potential engineering strategies for crop protection.

Indexed as

Plant ImmunityDisease ResistanceEvolution, MolecularHost-Pathogen InteractionsImmunity, InnateModels, ImmunologicalNLR ProteinsPlant DiseasesPlant ProteinsSignal TransductionNLR ProteinsPlant ProteinseffectorETINLRpathogenplant immunityPTI

Identifiers

PMID33946790
PMCPMC8124997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.