Evidence map›Paper›PMID 33946740›Full record

ArticlePharmaceutics2021

Antifungal Activity of Novel Formulations Based on Terpenoid Prodrugs against

Suvidha Menon, Xiuyi Liang, Richa Vartak, Ketankumar Patel, Antonio Di Stefano, Ivana Cacciatore, Lisa Marinelli, Blase Billack

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Current issues in molecular biology · 2024
    Article
  3. Review
  4. Review
  5. Review
  6. SelectedMolecules (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Identification of bioactive compounds inJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Suvidha MenonDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Xiuyi LiangDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Richa VartakDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Ketankumar PatelDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Antonio Di StefanoDepartment of Pharmacy, "G. D'Annunzio" University of Chieti-Pescara, 66100 Chieti Scalo, Italy.ORCID 0000-0002-3042-2234
Ivana CacciatoreDepartment of Pharmacy, "G. D'Annunzio" University of Chieti-Pescara, 66100 Chieti Scalo, Italy.ORCID 0000-0001-6253-0443
Lisa MarinelliDepartment of Pharmacy, "G. D'Annunzio" University of Chieti-Pescara, 66100 Chieti Scalo, Italy.
Blase BillackDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.ORCID 0000-0001-7180-5955
St. John's University · USUniversity of Chieti-Pescara · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca FAR 2019
6 · The paper itself

Abstract

Carvacrol (CAR), a phenolic monoterpenoid, has been extensively investigated for its antimicrobial and antifungal activity. As a result of its poor physicochemical properties, water soluble carvacrol prodrugs (WSCPs) with improved water solubility were previously synthesized and found to possess antimicrobial activity. Here, three novel CAR analogs, WSCP1, WSCP2, and WSCP3, were tested against fluconazole (FLU)-sensitive and -resistant strains where they showed greater antifungal activity than CAR against

Indexed as

antifungalCandida albicanscarvacrolintravaginal formulationsminimum inhibitory concentration

Identifiers

PMID33946740
PMCPMC8146751
OpenAlexW3157939813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.