Evidence map›Paper›PMID 33946662›Full record

ReviewInternational journal of molecular sciences2021

Epigenetic Modifications Associated with Exposure to Endocrine Disrupting Chemicals in Patients with Gestational Diabetes Mellitus.

Mateusz Kunysz, Olimpia Mora-Janiszewska, Dorota Darmochwał-Kolarz

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. New Personalized Medicine Model for Medication Management.Journal of personalized medicine · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. A Review of Modulation of Gut Microbiota to Mitigate Gestational Diabetes: Implications for Maternal and Child Health.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Chemical Compounds and Ambient Factors Affecting Pancreatic Alpha-Cells Mass and Function: What Evidence?International journal of environmental research and public health · 2022
    Review
  15. Review
  16. Epigenetic Links between Microbiota and Gestational Diabetes.International journal of molecular sciences · 2022
    Review
  17. Early Life Interventions Can Shape Aging.Frontiers in endocrinology · 2022
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mateusz KunyszDepartment of Obstetrics and Gynecology, Medical College, University of Rzeszow, 35-959 Rzeszow, Poland.ORCID 0000-0002-2947-3675
Olimpia Mora-JaniszewskaDepartment of Obstetrics and Gynecology, Medical College, University of Rzeszow, 35-959 Rzeszow, Poland.
Dorota Darmochwał-KolarzDepartment of Obstetrics and Gynecology, Medical College, University of Rzeszow, 35-959 Rzeszow, Poland.
University of Rzeszów · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) remains a significant clinical and public health issue due to its increasing prevalence and the possibility for numerous short- and long-term complications. The growing incidence of GDM seems to coincide with the widespread use of endocrine disrupting chemicals (EDCs). The extensive production and common use of these substances in everyday life has resulted in constant exposure to harmful substances from the environment. That may result in epigenetic changes, which may manifest themselves also after many years and be passed on to future generations. It is important to consider the possible link between environmental exposure to endocrine disrupting chemicals (EDCs) during pregnancy, epigenetic mechanisms and an increased risk for developing gestational diabetes mellitus (GDM). This manuscript attempts to summarize data on epigenetic changes in pregnant women suffering from gestational diabetes in association with EDCs. There is a chance that epigenetic marks may serve as a tool for diagnostic, prognostic, and therapeutic measures.

Indexed as

Diabetes, GestationalDNA MethylationEndocrine DisruptorsEnvironmental ExposureEpigenesis, GeneticFemaleGene Expression RegulationHumansInfant, NewbornPregnancyEndocrine DisruptorsEDCsepigeneticsgestational diabetes mellitus

Identifiers

PMID33946662
PMCPMC8124363
OpenAlexW3157581845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.