Evidence map›Paper›PMID 33946648›Full record

Trial reportInternational journal of molecular sciences2021

Deep Transcranial Magnetic Stimulation Affects Gut Microbiota Composition in Obesity: Results of Randomized Clinical Trial.

Anna Ferrulli, Lorenzo Drago, Sara Gandini, Stefano Massarini, Federica Bellerba, Pamela Senesi, Ileana Terruzzi, Livio Luzi

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anna FerrulliDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, 20099 Milan, Italy.ORCID 0000-0002-8518-5547
Lorenzo DragoDepartment of Biomedical Sciences for Health, University of Milan, 20123 Milan, Italy.ORCID 0000-0002-5206-540X
Sara GandiniDepartment of Experimental Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-1348-4548
Stefano MassariniDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, 20099 Milan, Italy.ORCID 0000-0002-7070-253X
Federica BellerbaDepartment of Experimental Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Pamela SenesiDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, 20099 Milan, Italy.ORCID 0000-0003-0304-1564
Ileana TerruzziDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, 20099 Milan, Italy.
Livio LuziDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, 20099 Milan, Italy.ORCID 0000-0003-3183-0552
University of Milan · ITEuropean Institute of Oncology · ITMultiMedica · IT

Funding

IRCCS Multimedica Ricerca CorrenteMinistero della Salute RF-2011-02349303
6 · The paper itself

Abstract

Growing evidence highlights the crucial role of gut microbiota in affecting different aspects of obesity. Considering the ability of deep transcranial magnetic stimulation (dTMS) to modulate the cortical excitability, the reward system, and, indirectly, the autonomic nervous system (ANS), we hypothesized a potential role of dTMS in affecting the brain-gut communication pathways, and the gut microbiota composition in obesity. In a hospital setting, 22 subjects with obesity (5 M, 17 F; 44.9 ± 2.2 years; BMI 37.5 ± 1.0 kg/m

Indexed as

Gastrointestinal MicrobiomeAdultAgedAutonomic Nervous SystemBacteriaBiodiversityDNA, BacterialDouble-Blind MethodFecesFemaleHumansMaleMiddle AgedModels, BiologicalNorepinephrineObesityDNA, BacterialNorepinephrineRNA, Ribosomal, 16Sdeep transcranial magnetic stimulationgut microbiotanorepinephrineobesity

Identifiers

PMID33946648
PMCPMC8125086
OpenAlexW3157234486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.