Evidence map›Paper›PMID 33946643›Full record

ReviewMicroorganisms2021

Cracking the Challenge of Antimicrobial Drug Resistance with CRISPR/Cas9, Nanotechnology and Other Strategies in ESKAPE Pathogens.

Tanzeel Zohra, Muhammad Numan, Aamer Ikram, Muhammad Salman, Tariq Khan, Misbahud Din, Muhammad Salman, Ayesha Farooq, Afreenish Amir, Muhammad Ali

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Sensitizing carbapenem-resistant Klebsiella pneumoniae using a compact Cascade-Cas3 system.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Advances in CRISPR-Cas for Diagnosis and Treatment ofPathogens (Basel, Switzerland) · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Antibacterial activity and biosynthetic potential of Streptomyces sp. PBR19, isolated from forest rhizosphere soil of Assam.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  14. In Vitro Susceptibility of Clinical and Carrier Strains ofInternational journal of molecular sciences · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Tanzeel ZohraPublic Health Laboratories Division, National Institute of Health, Islamabad 45500, Pakistan.
Muhammad NumanLaboratory of Molecular Biology and Biotechnology, Environmental and Health Sciences, University of North Carolina, Greensboro, NC 27412, USA.
Aamer IkramPublic Health Laboratories Division, National Institute of Health, Islamabad 45500, Pakistan.ORCID 0000-0002-6440-750X
Muhammad SalmanPublic Health Laboratories Division, National Institute of Health, Islamabad 45500, Pakistan.
Tariq KhanDepartment of Biotechnology, University of Malakand Chakdara Dir Lower, Chakdara 18000, Pakistan.ORCID 0000-0002-9194-9240
Misbahud DinDepartment of Biotechnology, Quaid-i-Azam University Islamabad, Islamabad 45320, Pakistan.ORCID 0000-0002-6248-5942
Muhammad SalmanDepartment of Biotechnology, Sarhad University, Peshawar 24755, Pakistan.
Ayesha FarooqPublic Health Laboratories Division, National Institute of Health, Islamabad 45500, Pakistan.
Afreenish AmirPublic Health Laboratories Division, National Institute of Health, Islamabad 45500, Pakistan.
Muhammad AliDepartment of Biotechnology, Quaid-i-Azam University Islamabad, Islamabad 45320, Pakistan.ORCID 0000-0002-7835-0663
National Institute of Health · PKQuaid-i-Azam University · PKSarhad University of Science and Information Technology · PKUniversity of Malakand · PKUniversity of North Carolina at Greensboro · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is mushrooming as a silent pandemic. It is considered among the most common priority areas identified by both national and international agencies. The global development of multidrug-resistant strains now threatens public health care improvement by introducing antibiotics against infectious agents. These strains are the product of both continuous evolution and unchecked antimicrobial usage (AMU). The ESKAPE pathogens (

Indexed as

antibioticsantimicrobial resistancebacteriaESKAPE

Identifiers

PMID33946643
PMCPMC8145940
OpenAlexW3157906861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.