Evidence map›Paper›PMID 33946544›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Lung Transplantation: CT Assessment of Chronic Lung Allograft Dysfunction (CLAD).

Anne-Laure Brun, Marie-Laure Chabi, Clément Picard, François Mellot, Philippe A Grenier

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Post-lung transplant surveillance in 2026: current practice, variability, and the need for standardization.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
  4. Review
  5. Review
  6. DynamicJHLT open · 2025
    Article
  7. HyperpolarizedJHLT open · 2024
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anne-Laure BrunRadiology Department, Hôpital Foch, 92150 Suresnes, France.
Marie-Laure ChabiRadiology Department, Hôpital Foch, 92150 Suresnes, France.ORCID 0000-0003-2503-6002
Clément PicardRespiratory Department, Hôpital Foch, 92150 Suresnes, France.
François MellotRadiology Department, Hôpital Foch, 92150 Suresnes, France.
Philippe A GrenierDepartment of Clinical Research and Innovation, Hôpital Foch, 92150 Suresnes, France.ORCID 0000-0003-3745-0032
Hôpital Foch · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic lung allograft rejection remains one of the major causes of morbi-mortality after lung transplantation. The term Chronic Lung Allograft Dysfunction (CLAD) has been proposed to describe the different processes that lead to a significant and persistent deterioration in lung function without identifiable causes. The two main phenotypes of CLAD are Bronchiolitis Obliterans Syndrome (BOS) and Restrictive Allograft Syndrome (RAS), each of them characterized by particular functional and imaging features. These entities can be associated (mixed phenotype) or switched from one to the other. If CLAD remains a clinical diagnosis based on spirometry, computed tomography (CT) scan plays an important role in the diagnosis and follow-up of CLAD patients, to exclude identifiable causes of functional decline when CLAD is first suspected, to detect early abnormalities that can precede the diagnosis of CLAD (particularly RAS), to differentiate between the obstructive and restrictive phenotypes, and to detect exacerbations and evolution from one phenotype to the other. Recognition of early signs of rejection is crucial for better understanding of physiopathologic pathways and optimal management of patients.

Indexed as

chronic lung allograft dysfunctioncomputed tomography (CT) scanlung transplantation

Identifiers

PMID33946544
PMCPMC8147203
OpenAlexW3157668598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.