Evidence map›Paper›PMID 33946527›Full record

ArticleInternational journal of molecular sciences2021

ROS-Mediated Anti-Tumor Effect of Coptidis Rhizoma against Human Hepatocellular Carcinoma Hep3B Cells and Xenografts.

So Young Kim, Cheol Park, Min Yeong Kim, Seon Yeong Ji, Hyun Hwangbo, Hyesook Lee, Su Hyun Hong, Min Ho Han, Jin-Woo Jeong, Gi-Young Kim and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
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  7. An Ethanol Extract ofNutrients · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

So Young KimAnti-Aging Research Center, Dongeui University, Busan 47340, Korea.
Cheol ParkDivision of Basic Sciences, College of Liberal Studies, Dong-Eui University, Busan 47340, Korea.
Min Yeong KimAnti-Aging Research Center, Dongeui University, Busan 47340, Korea.
Seon Yeong JiAnti-Aging Research Center, Dongeui University, Busan 47340, Korea.
Hyun HwangboAnti-Aging Research Center, Dongeui University, Busan 47340, Korea.
Hyesook LeeAnti-Aging Research Center, Dongeui University, Busan 47340, Korea.
Su Hyun HongDepartment of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Korea.
Min Ho HanNational Marine Biodiversity Institute of Korea, Seocheon 33662, Korea.
Jin-Woo JeongNakdonggang National Institute of Biological Resources, Sangju 17104, Korea.ORCID 0000-0002-7549-4514
Gi-Young KimDepartment of Marine Life Sciences, School of Marine Biomedical Sciences, Jeju National University, Jeju 63243, Korea.ORCID 0000-0002-6878-0790
Chang-Gue SonInstitute of Bioscience & Integrative Medicine, Daejeon University, 176 split 75 Daedeokdae-ro Seo-gu, Daejeon 35235, Korea.
JaeHun CheongDepartment of Molecular Biology, Pusan National University, Busan 46241, Korea.
Yung Hyun ChoiAnti-Aging Research Center, Dongeui University, Busan 47340, Korea.ORCID 0000-0002-1454-3124
Dong-Eui University · KRDaejeon University · KRJeju National University · KRMarine Biodiversity Institute of Korea · KRNational Institute of Biological Resources · KRPusan National University · KR

Funding

Korea Basic Science Institute grant NRF-2020R1A6C101A201National Research Foundation of Korea NRF-2018R1A2B2005705National Research Foundation of Korea grant NRF-2020R1A2C1099910
6 · The paper itself

Abstract

Coptidis Rhizoma is the dried rhizome from the

Indexed as

AnimalsAntineoplastic Agents, PhytogenicApoptosisCarcinoma, HepatocellularCaspase 3Cell Line, TumorCoptisCoptis chinensisDrugs, Chinese HerbalFemaleHumansLiver NeoplasmsMiceMice, NudeReactive Oxygen SpeciesRhizomeAntineoplastic Agents, PhytogenicCaspase 3Coptidis rhizoma extractDrugs, Chinese HerbalReactive Oxygen SpeciesapoptosisautophagyCoptidis RhizomaHep3B cellsmigration

Identifiers

PMID33946527
PMCPMC8124566
OpenAlexW3159074389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.