SynthesisInternational journal of environmental research and public health2021
Correlation between Handgrip Strength and Depression in Older Adults-A Systematic Review and a Meta-Analysis.
Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Association Between Handgrip Strength and Suicidal Ideation: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- Instruments for measuring the neuromuscular function domain of vitality capacity in older persons: an umbrella review.European geriatric medicine · 2024Pooled it
- Synergistic Effect of Increased Total Protein Intake and Strength Training on Muscle Strength: A Dose-Response Meta-analysis of Randomized Controlled Trials.Sports medicine - open · 2022Pooled it
- Factors Associated with Depression and Anxiety in Adults ≥60 Years Old during the COVID-19 Pandemic: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Directional postural sway tendencies and static balance among community-dwelling older adults with depression and without cognitive impairment.Aging clinical and experimental research · 2025Trial
- [Esketamine Alleviates Postoperative Depressive Symptoms in Frail Elderly Patients Undergoing Thoracoscopic Radical Resection of Lung Cancer: A Randomized Double-Blind Controlled Trial].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Trial
- Association between NHHR and depression symptoms among U.S. adults with hypertension: a cross sectional.BMC cardiovascular disorders · 2026Article
- Handgrip strength across clinical conditions and health-related outcomes in older adults: a scoping review.Frontiers in aging · 2026Review
- Associations between muscle strength and mental health in older adults.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Association between lower limb strength, anxiety, and depression symptoms in older adults.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Association of physical fitness and overweight with mental and behavioural diagnoses in a population-based cohort of 156 202 young men.BMJ open sport & exercise medicine · 2026Article
- Association between abdominal muscle mass quantified by computed tomography and depression in middle-aged and older Korean men: a cross-sectional study of 2,877 cases.Frontiers in medicine · 2026Article
- Handgrip strength as an indicator of psychological status in hospitalized intensive care unit patients: a cross-sectional study.Frontiers in medicine · 2026Article
- Postoperative sarcopenia in older patients with hip fractures: incidence and associated risk factors in a retrospective cohort study.Frontiers in medicine · 2026Article
- Associations of Handgrip Strength with Bone Health and Mental Health in Postmenopausal Women: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- Cumulative handgrip strength and trajectories of depressive symptoms in older adults: evidence from two cohort studies.BMC public health · 2025Article
- Emotional state in patients after COVID-19 in relation to comprehensive rehabilitation, Brain-Derived neurotrophic factor, Irisin levels, and selected clinical factors.Scientific reports · 2025Article
- Handgrip Strength, Depression, Dementia, Cognitive Function, and Their Predictive Effect on Functional Independence in Older Adults.Medicina (Kaunas, Lithuania) · 2025Article
- Interplay of Physical Activity, Muscle Strength, and Depression in Cognitive Impairment among Korean Older Adults: A Cross-sectional Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- The simple task of lifting five kilograms serves as a predictor of age-related disorders in old adults.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression remains an important health problem among older adults and it may be correlated with the deterioration of physical fitness, whose chief indicator is hand grip strength (HGS). The aim of the study was to investigate the relationship between depression and HGS among older populations using the available literature.
methodsPubMed, Web of Science and Science Direct databases were searched. The inclusion criteria were as follows: written in English and published after 2009, subject age: ≥60 years, HGS measured using a hand dynamometer, assessment of the depressive symptoms using a validated tool. The following articles were excluded: studies conducted among institutionalized subjects and/or populations with a specific disease.
resultsThe total combined effect of 33 results presented in 16 studies included in the meta-analysis, converted to the correlation coefficient, was OEr = -0.148 (SE = 0.030, 95%CI: -0.206--0.091), indicating a weak, negative correlation between HGS and depressive symptoms.
conclusionsThe review of the literature and the meta-analysis demonstrated a relationship between low muscle strength and intensified depressive symptoms in older populations. Bearing in mind that depression is often unrecognized or underdiagnosed among older patients, lowered muscle strength should be an important sign for physicians and an incentive to screen them for depression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.