Evidence map›Paper›PMID 33946390›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Photophysical and Antibacterial Properties of Porphyrins Encapsulated inside Acetylated Lignin Nanoparticles.

Nidia Maldonado-Carmona, Tan-Sothea Ouk, Nicolas Villandier, Claude Alain Calliste, Mário J F Calvete, Mariette M Pereira, Stéphanie Leroy-Lhez

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review.International journal of molecular sciences · 2023
    Review
  4. Review
  5. Review
  6. Latest trends on photodynamic disinfection of Gram-negative bacteria: photosensitizer's structure and delivery systems.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nidia Maldonado-CarmonaPEIRENE Laboratory, Faculty of Sciences and Techniques, University of Limoges, 87060 Limoges, France.ORCID 0000-0001-9109-8434
Tan-Sothea OukPEIRENE Laboratory, Faculty of Sciences and Techniques, University of Limoges, 87060 Limoges, France.ORCID 0000-0001-8576-5106
Nicolas VillandierPEIRENE Laboratory, Faculty of Sciences and Techniques, University of Limoges, 87060 Limoges, France.
Claude Alain CallistePEIRENE Laboratory, Faculty of Pharmacy, University of Limoges, 87025 Limoges, France.ORCID 0000-0002-4349-6785
Mário J F CalveteCoimbra Chemistry Center, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0003-2094-4781
Mariette M PereiraCoimbra Chemistry Center, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0003-4958-7677
Stéphanie Leroy-LhezPEIRENE Laboratory, Faculty of Sciences and Techniques, University of Limoges, 87060 Limoges, France.ORCID 0000-0002-6933-1372

Funding

H2020 Marie Skłodowska-Curie Actions 764837
6 · The paper itself

Abstract

Lignin has recently attracted the attention of the scientific community, as a suitable raw material for biomedical applications. In this work, acetylated lignin was used to encapsulate five different porphyrins, aiming to preserve their photophysical properties, and for further use as antibacterial treatment. The obtained nanoparticles were physically characterized, through dynamic light scattering size measurement, polydispersity index and zeta potential values. Additionally, the photophysical properties of the nanoparticles, namely UV-vis absorption, fluorescence emission, singlet oxygen production and photobleaching, were compared with those of the free porphyrins. It was found that all the porphyrins were susceptible to encapsulation, with an observed decrease in their fluorescence quantum yield and singlet oxygen production. These nanoparticles were able to exert an effective photodynamic bactericide effect (blue-LED light, 450-460 nm, 15 J/cm

Indexed as

lignin valorizationphotodynamic therapytetrapyrrolic compounds

Identifiers

PMID33946390
PMCPMC8147155

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.