ReviewInternational journal of molecular sciences2021
Physiology of Cerebellar Reserve: Redundancy and Plasticity of a Modular Machine.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Article
- Mistakes matter, age doesn't: task outcome modulates implicit motor adaptation similarly in young and older adults.GeroScience · 2026Article
- Cerebellar Network Compensation in Parkinson's Disease: Functional Connectivity Across Motor and Cognitive Circuits.medRxiv : the preprint server for health sciences · 2026Article
- Age-Related Low Frequency Amplitude Differences in Resting-State Blood Oxygenation Level-Dependent Signal in the Cerebellum.Human brain mapping · 2026Article
- Cerebellar clinical syndromes: the triad and rating scales.Journal of neurology · 2026Review
- Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026Review
- Cerebellar syndromes: clinical observations leading to the recognition of the three types.Arquivos de neuro-psiquiatria · 2025Review
- Glial Cells and Aging: From the CNS to the Cerebellum.International journal of molecular sciences · 2025Review
- Continuous theta burst stimulation to the medial posterior cerebellum impairs reversal learning in healthy volunteers.Cognitive, affective & behavioral neuroscience · 2025Article
- Characteristics of Cognitive Event-Related Potential Components and N170 Source Analysis in Patients with Acute Cerebellar Infarction.Cerebellum (London, England) · 2025Article
- Bimanual coordinated motor skill learning in patients with a chronic cerebellar stroke.Experimental brain research · 2024Article
- Review
- Consensus Paper: Cerebellum and Ageing.Cerebellum (London, England) · 2024Review
- Article
- Development of Cerebellar Reserve.Cells · 2022Article
- Environmental Enrichment Enhances Cerebellar Compensation and Develops Cerebellar Reserve.International journal of environmental research and public health · 2022Review
- Silas Weir Mitchell on the Cerebellum: Rich Neurophysiological Concepts and a Modern Perspective.Cerebellum (London, England) · 2022Review
- Cerebellum and Neurorehabilitation in Emotion with a Focus on Neuromodulation.Advances in experimental medicine and biology · 2022Article
- New prospects on cerebellar reserve: Remarks on neuroprotective effects of experience in animals and humans.Frontiers in systems neuroscience · 2022Review
- The underpinnings of cerebellar ataxias.Clinical neurophysiology practice · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cerebellum is endowed with the capacity for compensation and restoration after pathological injury, a property known as cerebellar reserve. Such capacity is attributed to two unique morphological and physiological features of the cerebellum. First, mossy fibers that convey peripheral and central information run mediolaterally over a wide area of the cerebellum, resulting in the innervation of multiple microzones, commonly known as cerebellar functional units. Thus, a single microzone receives redundant information that can be used in pathological conditions. Secondly, the circuitry is characterized by a co-operative interplay among various forms of synaptic plasticity. Recent progress in understanding the mechanisms of redundant information and synaptic plasticity has allowed outlining therapeutic strategies potentiating these neural substrates to enhance the cerebellar reserve, taking advantage of the unique physiological properties of the cerebellum which appears as a modular and potentially reconfiguring brain structure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.