Evidence map›Paper›PMID 33946340›Full record

ReviewInternational journal of molecular sciences2021

Chromatin Remodeling in the Brain-a

Sarah Larrigan, Sujay Shah, Alex Fernandes, Pierre Mattar

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah LarriganDepartment of Cell and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Sujay ShahDepartment of Cell and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID 0000-0002-5520-7426
Alex FernandesDepartment of Cell and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID 0000-0003-2995-5452
Pierre MattarDepartment of Cell and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID 0000-0002-5708-6218
University of Ottawa · CA

Funding

CIHR PJT 166032
6 · The paper itself

Abstract

During brain development, the genome must be repeatedly reconfigured in order to facilitate neuronal and glial differentiation. A host of chromatin remodeling complexes facilitates this process. At the genetic level, the non-redundancy of these complexes suggests that neurodevelopment may require a lexicon of remodelers with different specificities and activities. Here, we focus on the nucleosome remodeling and deacetylase (NuRD) complex. We review NuRD biochemistry, genetics, and functions in neural progenitors and neurons.

Indexed as

Chromatin Assembly and DisassemblyAnimalsBrainHumansMi-2 Nucleosome Remodeling and Deacetylase ComplexNeural Stem CellsNeurogenesisNeuronsMi-2 Nucleosome Remodeling and Deacetylase Complexautism spectrum disorderchromatin remodelinggliogenesisintellectual disabilityneurodevelopmentneurogenesisNuRD

Identifiers

PMID33946340
PMCPMC8125410
OpenAlexW3157692177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.