Evidence map›Paper›PMID 33946248›Full record

ArticleInternational journal of molecular sciences2021

Physiological Roles of the Rapidly Activated Delayed Rectifier K

Wei Hu, Robert B Clark, Wayne R Giles, Erwin Shibata, Henggui Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Wei HuBiological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester M13 9PL, UK.
Robert B ClarkDepartment of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Wayne R GilesDepartment of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Erwin ShibataDepartment of Physiology, Carver School of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Henggui ZhangBiological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester M13 9PL, UK.
University of Calgary · CAUniversity of Manchester · GBUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Robust, spontaneous pacemaker activity originating in the sinoatrial node (SAN) of the heart is essential for cardiovascular function. Anatomical, electrophysiological, and molecular methods as well as mathematical modeling approaches have quite thoroughly characterized the transmembrane fluxes of Na

Indexed as

Action PotentialsAnimalsCations, MonovalentCells, CulturedDelayed Rectifier Potassium ChannelsHeartIon TransportMiceModels, CardiovascularMyocytes, CardiacPacemaker, ArtificialPotassiumRabbitsSodium-Calcium ExchangerCations, MonovalentDelayed Rectifier Potassium ChannelsPotassiumSodium-Calcium ExchangerIKrK+ currentsmathematical modelingmouse heartrapid delayed rectifierrepolarizationSANsino-atrial nodespontaneous pacemaker activity

Identifiers

PMID33946248
PMCPMC8124469
OpenAlexW3159488233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.