Evidence map›Paper›PMID 33945867›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Prevalence of COVID-19 in children, adolescents and adults in remote education situations in the city of Fortaleza, Brazil.

Valdester Cavalcante Pinto Júnior, Luiz Francisco Wemmenson Gonçalves Moura, Rodrigo Cardoso Cavalcante, José Rubens Costa Lima, Arnaldo Solheiro Bezerra, Daylana Régia de Sousa Dantas, Cícero Matheus Lima Amaral, Daniel Freire Lima, Antonio Brazil Viana Júnior, Maria Izabel Florindo Guedes

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Valdester Cavalcante Pinto JúniorNortheast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil. Electronic address: incorcrianca@yahoo.com.br.
Luiz Francisco Wemmenson Gonçalves MouraBiotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil.
Rodrigo Cardoso CavalcanteDepartment of Medical Education, Nicklaus Children's Hospital, Miami, FL, USA.
José Rubens Costa LimaDr. Rocha Furtado Death Verification Service, Fortaleza, CE, Brazil.
Arnaldo Solheiro BezerraNortheast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil.
Daylana Régia de Sousa DantasNortheast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil.
Cícero Matheus Lima AmaralNortheast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil.
Daniel Freire LimaNortheast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil.
Antonio Brazil Viana JúniorClinical Research Unit CH-Federal University of Ceará/EBSERH, CE, Brazil.
Maria Izabel Florindo GuedesBiotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil.
Universidade Estadual do Ceará · BRMiami Children's Hospital · USUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA retrospective study was conducted to identify the prevalence of COVID-19 through serology and RT-PCR in children, adolescents and adults. A database of the COVID-19 Tracking Program in school children was used.

methodsThe data comprised sociodemographic and clinical variables, results of serological tests (IgM and IgG), and real-time-polymerase chain reaction (RT-PCR) results of IgM-positive individuals. The statistical analysis was performed with a 5% significance level.

resultsAmong 423 children, 107 (25.3%) exhibited seroprevalence with IgG, IgM or IgG/IgM; among 854 adolescents, 250 (29.2%) had positive serology; and among 282 adults, 59 (20.9%) were positive. The frequency of positivity on RT-PCR for SARS-CoV-2 was 3.5%, 3.6% and 6.0% in children, adolescents and adults, respectively. Children had a lower incidence of symptoms than adolescents (p = 0.001) and adults (p = 0.003); the most frequent were fever, ageusia, anosmia, headache, dry cough, sore throat, muscle pain, runny nose, dyspnoea, and diarrhoea.

conclusionsThe prevalence rate for all groups was 26.7% in serology and 4.04% in RT-PCR. Children had lower rates of IgM and fewer symptoms compared with adolescents and adults. The data suggest the potential for transmissibility in all age groups.

Indexed as

COVID-19AdolescentAdultBrazilChildHumansPrevalenceRetrospective StudiesSARS-CoV-2Seroepidemiologic StudiesChildImmunodetectionMolecular diagnosisPublic healthSARS-CoV-2

Identifiers

PMID33945867
PMCPMC8088039
OpenAlexW3158799988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.