Evidence map›Paper›PMID 33945330›Full record

ArticleJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models.

Craig Beeson, Yuri K Peterson, Nathan Perron, Mausumi Bandyopadhyay, Cecile Nasarre, Gyda Beeson, Richard F Comer, Christopher C Lindsey, Rick G Schnellmann, Bärbel Rohrer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Craig BeesonDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Yuri K PetersonDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Nathan PerronDepartment of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
Mausumi BandyopadhyayDepartment of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
Cecile NasarreDepartment of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
Gyda BeesonDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Richard F ComerDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Christopher C LindseyDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Rick G SchnellmannDepartment of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona, USA.
Bärbel RohrerDepartment of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
Medical University of South Carolina · USUniversity of Arizona · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7M
Alternative Pathway of Complement Activation in Age-Related Macular DegenerationR01EY019320 · NEI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ROHRER, BAERBEL · 2010 to 2014
$2.1M
Complement Factor H Haplotypes and Smoking in Age-Related Macular DegenerationI01RX000444 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI Baerbel Rohrer · 2011 to 2026
–
BLR&D Research Career Scientist Award for Dr. Barbel RohrerIK6BX004858 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI Baerbel Rohrer · 2020 to 2026
–
BLRD VA IK6 BX004858NEI NIH HHS R01 EY019320NIEHS NIH HHS P30 ES006694RRD VA I01 RX000444
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAnimalsMiceMice, Inbred BALB CMitochondriaProtective AgentsRetinal Cone Photoreceptor CellsRetinal DegenerationRetinitis PigmentosaSmall Molecule LibrariesProtective AgentsSmall Molecule Librariescalcium stressChemBridge libraryeye dropspharmacophoreretinitis pigmentosa

Identifiers

PMID33945330
PMCPMC8328042
OpenAlexW3159522958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.