Evidence map›Paper›PMID 33945100›Full record

ArticleJapanese journal of radiology2021

Differentiation of pulmonary complications with extensive ground-glass attenuation on high-resolution CT in immunocompromised patients.

Yoshie Kunihiro, Nobuyuki Tanaka, Reo Kawano, Tsuneo Matsumoto, Taiga Kobayashi, Toshiaki Yujiri, Makoto Kubo, Toshikazu Gondo, Katsuyoshi Ito

Open access · hybridAbstract read
In one paragraph

Article in Japanese journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yoshie KunihiroDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan. kyoshie@yamaguchi-u.ac.jp.ORCID http://orcid.org/0000-0002-5730-211X
Nobuyuki TanakaDepartment of Radiology, National Hospital Organization Yamaguchi - Ube Medical Center, 685 Higashikiwa, Ube, Yamaguchi, 755-0241, Japan.
Reo KawanoCenter for Integrated Medical Research, Hiroshima University Hospital, Kasumi 1-2-3 Minami-ku, Hiroshima, 734-8551, Japan.
Tsuneo MatsumotoDepartment of Radiology, National Hospital Organization Yamaguchi - Ube Medical Center, 685 Higashikiwa, Ube, Yamaguchi, 755-0241, Japan.
Taiga KobayashiDepartment of Radiology, National Hospital Organization Yamaguchi - Ube Medical Center, 685 Higashikiwa, Ube, Yamaguchi, 755-0241, Japan.
Toshiaki YujiriDivision of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Makoto KuboDepartment of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Toshikazu GondoDivision of Pathology, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa, Kanagawa, 251-8550, Japan.
Katsuyoshi ItoDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Yamaguchi University · JPNational Sanyo Hospital · JPFujisawa City Hospital · JPHiroshima University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to compare the high-resolution CT (HRCT) findings of pulmonary infectious and noninfectious complications with extensive ground-glass attenuation (GGA) in immunocompromised patients. MATERIALS AND

methodsOne hundred fifty-two immunocompromised patients with pulmonary complications that showed extensive GGA (> 50% of the whole lung on HRCT) were included in this study. The diagnoses of the 152 patients were as follows: pneumocystis pneumonia (PCP), n = 82; drug-induced pneumonia, n = 38; bacterial pneumonia, n = 9; cytomegalovirus pneumonia, n = 6; idiopathic pneumonia syndrome, n = 6; diffuse alveolar hemorrhage (DAH), n = 4; fungal infection, n = 3; tuberculosis, n = 2 and pulmonary edema, n = 2. Two chest radiologists retrospectively evaluated the CT criteria, which consisted of 12 findings.

resultsThe nodule (p = 0.015), the bronchovascular bundle (BVB) thickening (p = 0.001), and the interlobular septum (ILS) thickening (p = 0.002) were significantly infrequent in PCP. The ILS thickening was significantly frequent in drug-induced pneumonia (p < 0.001) though it was also frequent in other noninfectious and infectious diseases. The BVB thickening was significantly frequent in bacterial pneumonia (p = 0.005). The nodule was significantly frequent in DAH (p = 0.049).

conclusionNodules, BVB thickening, and ILS thickening could be useful HRCT findings for the differential diagnosis of pulmonary complications in immunocompromised patients with extensive GGA.

Indexed as

Lung DiseasesTomography, X-Ray ComputedHumansImmunocompromised HostLungRetrospective StudiesGround-glass opacityImmunocompromised hostMultivariate analysisX-ray computed tomography

Identifiers

PMID33945100
PMCPMC8093369
OpenAlexW3158956463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.