Evidence map›Paper›PMID 33945012›Full record

ArticleParasitology research2021

Niosomal versus nano-crystalline ivermectin against different stages of Trichinella spiralis infection in mice.

Dalia A Elmehy, Marwa A Hasby Saad, Gamal M El Maghraby, Mona F Arafa, Nema A Soliman, Heba H Elkaliny, Dina I Elgendy

Abstract read
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In one paragraph

Article in Parasitology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Molecular and serological assessment of the therapeutic efficacy of Ivermectin Loaded nanoparticles onJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  7. Repurposing of Amiodarone for treatment of muscle phase of experimental trichinellosis spiralis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  8. A potential therapeutic effect of sea cucumberJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  9. Article
  10. Review
  11. Cytotoxic effects of ivermectin onFrontiers in microbiology · 2024
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dalia A ElmehyDepartment of Medical Parasitology, Faculty of Medicine, Tanta University, Tanta, Egypt. dalia.elmehy@med.tanta.edu.eg.ORCID http://orcid.org/0000-0001-5590-3424
Marwa A Hasby SaadDepartment of Medical Parasitology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Gamal M El MaghrabyDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
Mona F ArafaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
Nema A SolimanDepartment of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt.
Heba H ElkalinyDepartment of Histology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Dina I ElgendyDepartment of Medical Parasitology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ivermectin (IVM) is one of the competitive treatments used for trichinellosis. However, several studies linked its efficacy with early diagnosis and administration to tackle the intestinal phase with limited activity being recorded against encysted larvae. The aim of this study was to employ niosomes for enhancing effectiveness of oral IVM against different stages of Trichinella spiralis (T. spiralis) infection with reference to nano-crystalline IVM. Mice were randomized into four groups: group Ι, 15 uninfected controls; group ΙΙ, 30 infected untreated controls; group ΙΙΙ, 30 infected nano-crystalline IVM treated, and group ΙV, 30 infected niosomal IVM treated. All groups were equally subdivided into 3 subgroups; (a) treated on the 1

Indexed as

AnimalsAntiparasitic AgentsChromatography, High Pressure LiquidDiaphragmInflammationIvermectinJejunumLarvaLiposomesMaleMiceNanoparticlesRandom AllocationTrichinella spiralisTrichinellosisZoonosesAntiparasitic AgentsIvermectinLiposomesAngiogenesisInflammationIvermectinMallory stainsNiosomesOxidative stressTrichinellosis

Identifiers

PMID33945012
OpenAlexW3159782743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.