Evidence map›Paper›PMID 33944831›Full record

ArticleActa bio-medica : Atenei Parmensis2021

An unusual aggressive presentation of late onset sepsis due to Staphylococcus aureus MRSA producing Panton-Valentine Leukocidin in preterm neonate.

Letizia Capasso, Julia Cerullo, Andrea Lo Vecchio, Clara Coppola, Lorenza Lepore, Valentina Marra, Eleni Antonaki, Francesco Raimondi

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PubMed Full text at PMC Publisher
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Letizia CapassoNeonatology, Pediatrics. Departement of Translational Medical Science. University Federico II, Napoli, Italy.. letizia.capasso@gmail.com.
Julia CerulloNeonatology, Pediatrics. Departement of Translational Medical Science. University Federico II, Napoli, Italy. juliacerullo88@gmail.com.
Andrea Lo VecchioPediatric Infectious Diseases Unit. Departement of Translational Medical Science. University Federico II, Napoli, Italy.. andrealovecchio@gmail.com.
Clara CoppolaNeonatology, Pediatrics. Departement of Translational Medical Science. University Federico II, Napoli, Italy. claracoppola18@gmail.com.
Lorenza LeporeNeonatology, Pediatrics. Departement of Translational Medical Science. University Federico II, Napoli. Italy. lorenza.lepore@gmail.com.
Valentina MarraNeonatology, Pediatrics. Departement of Translational Medical Science. University Federico II, Via Pansini 5, 80131. Napoli. Italy. valmrra@libero.it.
Eleni AntonakiDepartment of Molecular Medicine and Medical Biotechnology - Division of Bacteriology and Mycology, University of Naples. Federico II, Naples, Italy. antele2006@hotmail.it.
Francesco RaimondiNeonatology, Pediatrics. Departement of Translational Medical Science. University Federico II, Napoli. Italy. raimondi@unina.it.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an unusual and rare case of infection from methicillin resistant Staphylococcus aureus (MRSA) producing Panton-Valentine leukocidin in a preterm neonate in NICU. On day of life 8, a preterm baby boy suddenly developed arthritis, giant cutaneous abscesses and an osteomyelitic focus with pour clinical condition. This very aggressive presentation of infection from MRSA push us to test Panton-Valentine leukocidin resulted positive and to test contacts to discover the bearer of the germ. MRSA producing Panton-Valentine leukocidin is an unusual case of infection in preterm neonate that has not been reported elsewhere. A very aggressive sepsis in neonates from Staphilococcus aureus should evoke the need to test Panton-Valentine leukocidin to rapidly establish an appropriate treatment. We underline also the importance to test contacts to establish promptly a decontaminant therapy.

Indexed as

Methicillin-Resistant Staphylococcus aureusSepsisStaphylococcal InfectionsBacterial ToxinsExotoxinsHumansInfant, NewbornLeukocidinsMaleStaphylococcus aureusBacterial ToxinsExotoxinsLeukocidinsPanton-Valentine leukocidin

Identifiers

PMID33944831
PMCPMC8142768
OpenAlexW3157724085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.