Evidence map›Paper›PMID 33942631›Full record

ArticleThe Journal of international medical research2021

Association between interleukin gene polymorphisms and susceptibility to gastric cancer in the Qinghai population.

Xiaoyan Song, Dongmei Wang, Baji Ben, Chenghua Xiao, Liyan Bai, Han Xiao, Wenyan Zhang, Wanchao Li, Jingying Jia, Yujuan Qi

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Role ofThe Journal of international medical research · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xiaoyan SongDepartment of Medical Oncology, Qinghai Provincial People's Hospital, Xining, China.
Dongmei WangDepartment of Oncology, Affiliated Hospital of Heze Medical College, Heze, China.
Baji BenDepartment of Medical Oncology, Qinghai Provincial People's Hospital, Xining, China.
Chenghua XiaoDepartment of Medical Oncology, Qinghai Provincial People's Hospital, Xining, China.
Liyan BaiDepartment of Medical Oncology, Qinghai Provincial People's Hospital, Xining, China.
Han XiaoDepartment of Medical Oncology, Qinghai University Affiliated Hospital, Xining, China.
Wenyan ZhangDepartment of Medical Oncology, Qinghai Provincial People's Hospital, Xining, China.
Wanchao LiDepartment of Oncology, Affiliated Hospital of Heze Medical College, Heze, China.
Jingying JiaDepartment of Oncology, Affiliated Hospital of Heze Medical College, Heze, China.
Yujuan QiDepartment of Medical Oncology, Qinghai Provincial People's Hospital, Xining, China.ORCID https://orcid.org/0000-0002-0098-6813
Qinghai Provincial Peoples Hospital · CNHeze Medical College · CNQinghai University Affiliated Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the associations between interleukin (IL) gene polymorphisms and susceptibility to gastric cancer in the Qinghai population, China.

methodsPatients with gastric cancer and cancer-free controls were enrolled into the study from Qinghai Provincial People's Hospital between September 2016 and September 2018. Single nucleotide polymorphisms (SNPs) were genotyped with the Sequenom MassARRAY® SNP genotype system. The Hardy-Weinberg equilibrium in allele and genotype frequencies, and general characteristics between patients with gastric cancer and cancer-free controls, were evaluated using χ

resultsAmong eight candidate SNPs, the allele and genotype frequency distribution of IL-1B rs1143634 polymorphism was significantly different between patients with gastric cancer (

conclusionThe IL-1B rs1143634 polymorphism might be associated with a decreased risk of gastric cancer, and may be a protective factor against gastric cancer.

Indexed as

Stomach NeoplasmsCase-Control StudiesChinaGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansInterleukinsPolymorphism, Single NucleotideInterleukinscancer riskGastric cancerIL-1B rs1143634interleukin (IL) genespolymorphismssusceptibility

Identifiers

PMID33942631
PMCPMC8113958
OpenAlexW3157178283

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.