ArticleJournal of the American Heart Association2021
Acute Exposure to Diesel Exhaust Increases Muscle Sympathetic Nerve Activity in Humans.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Epidemiological and mechanistic links between PMFrontiers in endocrinology · 2025Pooled it
- Effects of respirators to reduce fine particulate matter exposures on blood pressure and heart rate variability: A systematic review and meta-analysis.Environmental pollution (Barking, Essex : 1987) · 2022Pooled it
- Black carbon as a major contributor to ambient PMEco-Environment & Health · 2026Article
- Sympathetic Neural Overactivation, Vascular Dysfunction, and Exercise Intolerance in Long-Term Survivors of Breast Cancer Treated With Doxorubicin and Trastuzumab-Based Chemotherapy.Journal of the American Heart Association · 2026Article
- Risk of BPH-LUTS according to the PM₁₀ exposure: A longitudinal nationwide cohort-based study.Investigative and clinical urology · 2026Article
- Effects of Outdoor and Household Air Pollution on Hand Grip Strength in a Longitudinal Study of Rural Beijing Adults.International journal of environmental research and public health · 2025Article
- Air Pollution and Stroke: An Emerging Challenge From Cardio-Cerebrovascular Multimorbidity.Journal of the American Heart Association · 2025Review
- Acute airway inflammation following controlled biodiesel exhaust exposure in healthy subjects.Particle and fibre toxicology · 2024Article
- Exploring the impact of occupational exposure: A study on cardiovascular autonomic functions of male gas station attendants in Sri Lanka.Physiological reports · 2024Article
- Controlled human exposures: a review and comparison of the health effects of diesel exhaust and wood smoke.Particle and fibre toxicology · 2024Review
- Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions.Circulation research · 2024Review
- HIPTox-Hazard Identification Platform to Assess the Health Impacts from Indoor and Outdoor Air Pollutant Exposures, through Mechanistic Toxicology: A Single-Centre Double-Blind Human Exposure Trial Protocol.International journal of environmental research and public health · 2024Article
- Noise and Air Pollution as Risk Factors for Hypertension: Part II-Pathophysiologic Insight.Hypertension (Dallas, Tex. : 1979) · 2023Review
- If you don't kill pollution it could kill you: pathophysiologic insights into pollution mediated cardiovascular risk through FDG PET imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Correlation between Graphitic Carbon and Elemental Carbon in Diesel Particulate Matter in Workplace Atmospheres.Analytical chemistry · 2023Article
- Body Mass Index Modulates the Impact of Short-Term Exposure to Air Particulate Matter on High-Density Lipoprotein Function.Antioxidants (Basel, Switzerland) · 2022Article
- Associations between short-term exposure to PMOpen heart · 2022Article
- Associations of air pollution with peripheral inflammation and cardiac autonomic physiology in children.New directions for child and adolescent development · 2022Article
- Adrenergic and Glucocorticoid Receptors in the Pulmonary Health Effects of Air Pollution.Toxics · 2021Review
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Diesel exhaust (DE) emissions are a major contributor to ambient air pollution and are strongly associated with cardiovascular morbidity and mortality. Exposure to traffic-related particulate matter is linked with acute adverse cardiovascular events; however, the mechanisms are not fully understood. We examined the role of the autonomic nervous system during exposure to DE that has previously only been indirectly investigated. Methods and Results Using microneurography, we measured muscle sympathetic nerve activity (MSNA) directly in the peroneal nerve of 16 healthy individuals. MSNA, heart rate, and respiration were recorded while subjects rested breathing filtered air, filtered air with an exposure mask, and standardized diluted DE (300 µg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.