ArticleBrain and behavior2021
Atrial cardiopathy in embolic stroke of undetermined source.
Article in Brain and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Echocardiographic Characteristics of Patients with Multiple Acute Concomitant Cerebral Infarcts.Journal of clinical medicine · 2025Article
- Atrial Cardiomyopathy: From Diagnosis to Treatment.Reviews in cardiovascular medicine · 2025Review
- Role of STK38L in atrial fibrillation-associated myocardial fibrosis: findings from RNA-seq analysis.Cardiovascular diagnosis and therapy · 2024Article
- Circulating exosome long non-coding RNAs are associated with atrial structural remodeling by increasing systemic inflammation in atrial fibrillation patients.Journal of translational internal medicine · 2024Article
- P-wave indices and left atrial mechanics as predictors of atrial cardiopathy in embolic stroke of undetermined source.Scientific reports · 2023Observational
- Evaluation of lncRNA Expression Pattern and Potential Role in Heart Failure Pathology.Disease markers · 2023Article
- Arterial Hypertension and Its Consequences Are the Main Predictors of Embolic Stroke of Undetermined Source.Disease markers · 2023Article
- Atrial cardiomyopathy: from cell to bedside.ESC heart failure · 2022Review
- Review and update of the concept of embolic stroke of undetermined source.Nature reviews. Neurology · 2022Review
- Atrial cardiopathy in embolic stroke of undetermined source.Brain and behavior · 2021Article
- Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAtrial cardiopathy is one of the most common potential sources of thromboembolism for embolic stroke of undetermined source (ESUS). The study aims to investigate the incidence of atrial cardiopathy (defined by severe left atrial enlargement (sLAE) or elevated serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) > 250 pg/ml) in patients with ESUS and compare with other stroke subtypes.
methodsWe retrospectively collected data of 936 consecutive patients with diffusion-weighted imaging-confirmed acute ischemic stroke. The incidence of atrial cardiopathy was examined in ESUS, large artery atherosclerosis (LAA), and small vessel disease (SVD) strokes. Clinical characteristics were compared between ESUS patients with atrial cardiopathy (AC-ESUS) and patients with atrial fibrillation-induced cardioembolism (AF-CE) stroke.
results245 patients were diagnosed with ESUS, while others were diagnosed with LAA (n = 312), SVD (n = 258), and AF-CE (n = 121) strokes. The incidence of sLAE in ESUS patients was higher than in LAA or SVD group (5.3% vs. 1.6% and 1.2%, respectively, p = .005) and higher than in combined LAA/SVD group (5.3% vs. 1.4%, p = .001). The incidence of elevated serum NT-proBNP in ESUS patients was not statistically different from that in LAA or SVD group. Compared with patients with AF-CE stroke, AC-ESUS patients had milder manifestations, had less hemorrhagic transformation, had better short-term outcome, and had fewer in-hospital complications.
conclusionsThe incidence of sLAE was higher in ESUS patients than in patients with noncardioembolic strokes. AC-ESUS was milder when compared to AF-CE stroke.
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