Evidence map›Paper›PMID 33942372›Full record

ArticleNeurourology and urodynamics2021

Is coronavirus disease 2019 associated with indicators of long-term bladder dysfunction?

Blayne Welk, Lucie Richard, Emmanuel Braschi, Marcio A Averbeck

Open access · bronzeAbstract read
In one paragraph

Article in Neurourology and urodynamics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Long COVID and COVID-19-associated cystitis (CAC).International urology and nephrology · 2022
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Blayne WelkDepartment of Surgery, Epidemiology and Biostatistics, Western University, London, Canada.ORCID 0000-0001-7093-558X
Lucie RichardICES Western, London, Canada.
Emmanuel BraschiDepartment of Urology, Instituto Nacional de Rehabilitación Psicofísica del Sur, Mar del Plata, Argentina.
Marcio A AverbeckDepartment of Urology, Moinhos de Vento Hospital, Porto Alegre, Brazil.
Western University · CAHospital Moinhos de Vento · BRInstituto Nacional de Rehabilitación Psicofísica · AR

Funding

St. Joseph's Health Care Foundation's Health Crisis Fund NA
6 · The paper itself

Abstract

objectiveEarly reports have suggested that coronavirus disease 2019 (COVID-19) can present with significant urinary frequency and nocturia, and that these symptoms correlate with markers of inflammation in the urine. We evaluated surrogate markers of chronic urinary symptoms to determine if they were more frequent after COVID-19 infection.

methodsRoutinely collected data from the province of Ontario was used to conduct a matched, retrospective cohort study. We identified patients 66 years of age or older who had a positive COVID-19 test between February and May 2020 and survived at least 2 months after their diagnosis. We matched them to two similar patients who did not have a positive COVID-19 test during the same time period. We measured the frequency of urology consultation, cystoscopy, and new prescriptions for overactive bladder medications during a subsequent 3-month period. Proportional hazard models were adjusted for any baseline differences between the groups.

resultsWe matched 5617 patients with COVID-19 to 11,225 people who did not have COVID-19. The groups were similar, aside from a higher proportion of patients having hypertension and diabetes in the CoVID-19 cohort. There was no significantly increased hazard of new receipt of overactive bladder medication (hazards ratio [HR]: 1.04, p = 0.88), urology consultation (HR: 1.40, p = 0.10), or cystoscopy (HR: 1.14, p = 0.50) among patients who had COVID-19, compared to the matched cohort.

conclusionSurrogate markers of potential bladder dysfunction were not significantly increased in the 2-5 months after COVID-19 infection.

Indexed as

AgedCase-Control StudiesCohort StudiesCOVID-19FemaleHumansInflammation MediatorsMaleOntarioRetrospective StudiesSARS-CoV-2Urinary Bladder, OveractiveInflammation MediatorsCOVID-19lower urinary tract symptomsoveractiveSARS-CoV-2urinary bladder

Identifiers

PMID33942372
PMCPMC8242545
OpenAlexW3158501744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.