Evidence map›Paper›PMID 33942342›Full record

GuidelineHepatology (Baltimore, Md.)2021

Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases.

Scott W Biggins, Paulo Angeli, Guadalupe Garcia-Tsao, Pere Ginès, Simon C Ling, Mitra K Nadim, Florence Wong, W Ray Kim

Erratum issued Registry-linked trialOpen access · greenAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Hepatology (Baltimore, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06525623 (Initial Resuscitation for Acute Kidney Injury in Patients With Cirrhosis), which is not on this map. Cited by 406 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
406citing papers in PubMed, 7 pooled it
57.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06525623 narecruitingnot on this mapstarted 2024, after this paper: background citation

Initial Resuscitation for Acute Kidney Injury in Patients With Cirrhosis: A Pilot Randomized Trial Using a Volume Assessment Guidance Algorithm

TypeinterventionalSponsorMassachusetts General HospitalRan2024 to 2027Enrolled50ConditionsCirrhosis, Liver, Acute Kidney Injury, Hepatorenal SyndromeArmsRecommendation: No Further Resuscitation, Recommendation: Resuscitation with Crystalloid, Recommendation: Resuscitation with Colloid, Recommendation: Standard of Care IV Albumin
3 · Its place in the literature

Who cites it

406 citing papers in PubMed, 7 syntheses or guidelines pooled it, 745 citations in OpenAlex.

  1. Low-Dose vs. Standard Care Iv Human Albumin During Large-Volume Paracentesis in Patients With Liver Cirrhosis: A Systematic Review.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Pooled it
  3. [Chinese guidelines for clinical diagnosis, treatment, and management of cirrhosis (2025)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Guideline
  4. Pooled it
  5. [Guidelines for the diagnosis and treatment of acute-on-chronic liver failure (2025 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Guideline
  6. Guideline
  7. Guideline
  8. Trial
  9. Trial
  10. Trial
  11. Safety and efficacy of continuous infusion terlipressin (BIV201): A phase 2 trial in patients with decompensated cirrhosis and refractory ascites.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2025
    Trial
  12. Trial
  13. Article
  14. Article
  15. Article
  16. Influence of Albumin Treatment Duration on Outcome of Terlipressin Therapy in Patients With HRS-AKI.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Observational
  17. Machine learning-derived clinical phenotypes of ascites in cirrhosis: A multi-center latent class analysis with external validation.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Article
  18. Review
  19. Article
  20. Article

346 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 4 countries.

Scott W BigginsDivision of Gastroenterology and Hepatology, and Center for Liver Investigation Fostering discovEryUniversity of WashingtonSeattleWA.
Paulo AngeliUnit of Hepatic Emergencies and Liver TransplantationDepartment of MedicineDIMEDUniversity of PadovaPaduaItaly.
Guadalupe Garcia-TsaoDepartment of Internal MedicineSection of Digestive DiseasesYale UniversityNew HavenCT.
Pere GinèsLiver Unit, Hospital Clinic, and Institut d'Investigacions Biomèdiques August Pi i SunyerUniversity of BarcelonaBarcelonaSpain.ORCID 0000-0003-4657-4504
Simon C LingThe Hospital for Sick Children, Division of Gastroenterology, Hepatology and Nutrition, and Department of PaediatricsUniversity of TorontoTorontoOntarioCanada.
Mitra K NadimDivision of NephrologyUniversity of Southern CaliforniaLos AngelesCA.
Florence WongDivision of Gastroenterology and HepatologyUniversity Health NetworkUniversity of TorontoTorontoOntarioCanada.ORCID 0000-0001-9263-8869
W Ray KimDivision of Gastroenterology and HepatologyStanford UniversityPalo AltoCA.ORCID 0000-0002-3030-860
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · ESStanford University · USUniversity Health Network · CAUniversity of Padua · ITUniversity of Southern California · USUniversity of Toronto · CAUniversity of Washington · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AscitesEnd Stage Liver DiseaseGastroenterologyHepatorenal SyndromeHumansPeritonitis

Identifiers

PMID33942342
OpenAlexW3159795713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.