Evidence map›Paper›PMID 33942204›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021

Association between knee symptoms, change in knee symptoms over 6-9 years, and SF-6D health state utility among middle-aged Australians.

Ambrish Singh, Julie A Campbell, Alison Venn, Graeme Jones, Leigh Blizzard, Andrew J Palmer, Terence Dwyer, Flavia Cicuttini, Changhai Ding, Benny Antony

Abstract read
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In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Imaging and Biochemical Markers for Osteoarthritis.Diagnostics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Ambrish SinghMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.ORCID http://orcid.org/0000-0002-4618-7507
Julie A CampbellMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Alison VennMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Graeme JonesMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Leigh BlizzardMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Andrew J PalmerMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Terence DwyerMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Flavia CicuttiniDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
Changhai DingMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Benny AntonyMenzies Institute for Medical Research, University of Tasmania, Hobart, Australia. Benny.EathakkattuAntony@utas.edu.au.
University of Tasmania · AUMonash University · AU

Funding

National Health and Medical Research Council 211316Royal Hobart Hospital Research Foundation 18-202 RHHRF
6 · The paper itself

Abstract

objectivesHealth state utilities (HSUs) are an input metric for estimating quality-adjusted life-years (QALY) in cost-utility analyses. Currently, there is a paucity of data on association of knee symptoms with HSUs for middle-aged populations. We aimed to describe the association of knee symptoms and change in knee symptoms with SF-6D HSUs and described the distribution of HSUs against knee symptoms' severity.

methodsParticipants (36-49-years) were selected from the third follow-up (completed 2019) of Australian Childhood Determinants of Adult Health study. SF-6D HSUs were generated from the participant-reported SF-12. Association between participant-reported WOMAC knee symptoms' severity, change in knee symptoms over 6-9 years, and HSUs were evaluated using linear regression models.

resultsFor the cross-sectional analysis, 1,567 participants were included; mean age 43.5 years, female 54%, BMI ± SD 27.18 ± 5.31 kg/m

conclusionIn a middle-aged population-based sample, there was an independent negative association between worse knee symptoms and SF-6D HSUs. Our findings may be used by decision-makers to define more realistic and conservative baseline and ongoing HSU values when assessing QALY changes associated with osteoarthritis interventions.

Indexed as

Quality of LifeAdultAustraliaChildCost-Benefit AnalysisCross-Sectional StudiesFemaleHumansMiddle AgedQuality-Adjusted Life YearsSurveys and QuestionnairesHealth state utilityOsteoarthritisPopulation normQALYSF-6DWOMAC

Identifiers

PMID33942204
OpenAlexW3157118090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.