Evidence map›Paper›PMID 33942077›Full record

ArticleThe Journal of clinical endocrinology and metabolism2021

National Trends in Pediatric Admissions for Diabetic Ketoacidosis, 2006-2016.

Estelle M Everett, Timothy P Copeland, Tannaz Moin, Lauren E Wisk

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

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  16. Diabetic Ketoacidosis and Long-term Insulin Requirements in Youths with Newly Diagnosed Type 2 Diabetes During the SARS-CoV-2 Pandemic.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Estelle M EverettDivision of Endocrinology, Diabetes, & Metabolism, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID 0000-0002-7468-296X
Timothy P CopelandDepartment of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles, California, USA.
Tannaz MoinDivision of Endocrinology, Diabetes, & Metabolism, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID 0000-0002-5035-6641
Lauren E WiskDivision of General Internal Medicine & Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID 0000-0003-2932-4140
University of California, Los Angeles · US

Funding

A Cluster-Randomized Trial of Pharmacist-Coordinated Implementation of the DPPR18DK105464 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DURU, OBIDIUGWU KENRIK, MANGIONE, CAROL M · 2015 to 2019
$3.3M
Delivering contextualizing population data to patients to motivate health care transition preparationK01DK116932 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WISK, LAUREN ELISABETH · 2018 to 2023
$647k
ACL HHS U18DP006535CDC HHS U18DP006535NIDDK NIH HHS K01 DK116932NIDDK NIH HHS K01DK116932NIDDK NIH HHS R18 DK105464NIH HHS R18DK105464Patient-Centered Outcomes Research Institute SDM-2018C2-13543VA QUE15-272
6 · The paper itself

Abstract

BACKGROUND AND

objectivesDiabetic ketoacidosis (DKA) rates in the United States are rising. Prior studies suggest higher rates in younger populations, but no studies have evaluated national trends in pediatric populations and differences by subgroups. As such, we sought to examine national trends in pediatric DKA.

methodsWe used the 2006, 2009, 2012, and 2016 Kids' Inpatient Database to identify pediatric DKA admissions among a nationally representative sample of admissions of youth ≤20 years old. We estimate DKA admission per 10 000 admissions and per 10 000 population, charges, length of stay (LOS), and trends over time among all hospitalizations and by demographic subgroups. Regression models were used to evaluate differences in DKA rates within subgroups overtime.

resultsBetween 2006 and 2016, there were 149 535 admissions for DKA. Unadjusted DKA rate per admission increased from 120.5 (95% CI, 115.9-125.2) in 2006 to 217.7 (95% CI, 208.3-227.5) in 2016. The mean charge per admission increased from $14 548 (95% CI, $13 971-$15 125) in 2006 to $20 997 (95% CI, $19 973-$22 022) in 2016, whereas mean LOS decreased from 2.51 (95% CI, 2.45-2.57) to 2.28 (95% CI, 2.23-2.33) days. Higher DKA rates occurred among 18- to 20-year-old females, Black youth, without private insurance, with lower incomes, and from nonurban areas. Young adults, men, those without private insurance, and from nonurban areas had greater increases in DKA rates across time.

conclusionsPediatric DKA admissions have risen by 40% in the United States and vulnerable subgroups remain at highest risk. Further studies should characterize the challenges experienced by these groups to inform interventions to mitigate their DKA risk and to address the rising DKA rates nationally.

Indexed as

AdolescentChildChild, PreschoolDatabases, FactualDiabetic KetoacidosisFemaleHumansInfantLength of StayMalePatient AdmissionUnited StatesYoung Adultdiabetic ketoacidosisdisparitiespediatricstype 1 diabetes

Identifiers

PMID33942077
PMCPMC8277205
OpenAlexW3159693641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.