Evidence map›Paper›PMID 33941897›Full record

ArticleNature biomedical engineering2021

A soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure.

Joohee Kim, Jihun Park, Young-Geun Park, Eunkyung Cha, Minjae Ku, Hyeon Seok An, Kyoung-Pil Lee, Man-Il Huh, Junmo Kim, Taek-Soo Kim and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 208 citations in OpenAlex.

  1. Article
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  3. Bioinspired Photodetectors: From Nature to Advanced Applications.Advanced materials (Deerfield Beach, Fla.) · 2026
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  9. Ion-Pair-Tuned Ionogels for Broad-Range Linear Pressure Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  10. Article
  11. Mechanomedicine.Nature reviews bioengineering · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  17. Unperceivable Designs of Wearable Electronics.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  18. Review
  19. Article
  20. Review

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Joohee Kim *Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-0294-9565
Jihun Park *Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-4402-6881
Young-Geun ParkDepartment of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-1579-0220
Eunkyung ChaDepartment of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
Minjae KuDepartment of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
Hyeon Seok AnDepartment of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
Kyoung-Pil LeeDepartment of Ophthalmology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Man-Il HuhDepartment of Ophthalmology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Junmo KimDepartment of Mechanical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Taek-Soo KimDepartment of Mechanical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Dai Woo KimDepartment of Ophthalmology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. proector97@gmail.com.ORCID http://orcid.org/0000-0001-9155-5092
Hong Kyun KimDepartment of Ophthalmology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. okeye@knu.ac.kr.ORCID http://orcid.org/0000-0002-9283-3506
Jang-Ung ParkDepartment of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea. jang-ung@yonsei.ac.kr.ORCID http://orcid.org/0000-0003-1522-4958
Yonsei University · KRKyungpook National University · KRKorea Advanced Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous detection of raised intraocular pressure (IOP) could benefit the monitoring of patients with glaucoma. Current contact lenses with embedded sensors for measuring IOP are rigid, bulky, partially block vision or are insufficiently sensitive. Here, we report the design and testing in volunteers of a soft and transparent contact lens for the quantitative monitoring of IOP in real time using a smartphone. The contact lens incorporates a strain sensor, a wireless antenna, capacitors, resistors, stretchable metal interconnects and an integrated circuit for wireless communication. In rabbits, the lens provided measurements that match those of a commercial tonometer. In ten human participants, the lens proved to be safe, and reliably provided accurate quantitative measurements of IOP without inducing inflammation.

Indexed as

AdultAnimalsCattleCell PhoneContact LensesFemaleHumansIntraocular PressureMonitoring, PhysiologicPrinting, Three-DimensionalRabbitsWireless Technology

Identifiers

PMID33941897
OpenAlexW3157186650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.