Evidence map›Paper›PMID 33941850›Full record

ArticleLeukemia2021

A dose substitution of anthracycline intensity with dose-dense rituximab in children and adolescents with good-risk mature B-cell lymphoma.

Stan Goldman, Matthew Barth, Bruce Shiramizu, Qiuhu Shi, Jessica Hochberg, Liana Klejmont, Lauren Harrison, Jackie Basso, Yaya Chu, Humayun Islam and 11 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01859819 (Reduced Burden of Oncologic Therapy in Advanced B-cell Lymphoma), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01859819 phase2completednot on this map

Reduced Burden of Oncologic Therapy in Advanced B-cell Lymphoma (REBOOT ABLY) in Children, Adolescents and Young Adults With CD20+ Mature B-Cell Lymphoma

TypeinterventionalSponsorNew York Medical CollegeRan2013 to 2021Enrolled45ConditionsDiffuse Large Cell Lymphoma, Burkitt's Lymphoma, High Grade B-cell LymphomaArmsRituximab, IT Cytarabine
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Haematologica · 2024
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Stan GoldmanDepartment of Pediatric Hematology/Oncology, Medical City Children's Hospital, Dallas, TX, USA.
Matthew BarthDepartment of Pediatrics, Roswell Park Cancer Institute, Buffalo, NY, USA.
Bruce ShiramizuDepartment of Tropical Medicine, Medical Microbiology & Pharmacology, University of Hawaii, Honolulu, HI, USA.
Qiuhu ShiDepartment of Biostatistics, New York Medical College, Valhalla, NY, USA.
Jessica HochbergDepartment of Pediatrics, New York Medical College, Valhalla, NY, USA.
Liana KlejmontDepartment of Pediatrics, New York Medical College, Valhalla, NY, USA.
Lauren HarrisonDepartment of Pediatrics, New York Medical College, Valhalla, NY, USA.
Jackie BassoDepartment of Pediatrics, New York Medical College, Valhalla, NY, USA.
Yaya ChuDepartment of Pediatrics, New York Medical College, Valhalla, NY, USA.
Humayun IslamDepartment of Pathology, New York Medical College, Valhalla, NY, USA.
Perry GerardDepartment of Radiology, New York Medical College, Valhalla, NY, USA.
Melissa Agsalda-GarciaDepartment of Tropical Medicine, Medical Microbiology & Pharmacology, University of Hawaii, Honolulu, HI, USA.
Tiffany ShiehDepartment of Tropical Medicine, Medical Microbiology & Pharmacology, University of Hawaii, Honolulu, HI, USA.
Javier OesterheldLevine Children's Hospital, Charlotte, NC, USA.
Kenneth HeymCook Children's Medical Center, Fort Worth, TX, USA.
Ivan KirovChildren's Hospital Orange County, Irvine, CA, USA.
Richard DrachtmanRutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Paul Harker-MurrayMedical College of Wisconsin, Milwaukee, WI, USA.
Sherrie PerkinsDepartment of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT, USA.
Rodney R MilesDepartment of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT, USA.
Mitchell CairoDepartment of Pediatrics, New York Medical College, Valhalla, NY, USA. Mitchell_Cairo@nymc.edu.ORCID http://orcid.org/0000-0002-2075-434X

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultAnthracyclinesAntineoplastic Combined Chemotherapy ProtocolsChildChild, PreschoolDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansLymphoma, B-CellMalePrognosisRituximabSurvival RateYoung AdultAnthracyclinesRituximab

Identifiers

PMID33941850
PMCPMC12582166

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.