Evidence map›Paper›PMID 33941706›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The voltage sensor is responsible for ΔpH dependence in H

Emerson M Carmona, Miguel Fernandez, Juan J Alvear-Arias, Alan Neely, H Peter Larsson, Osvaldo Alvarez, Jose Antonio Garate, Ramon Latorre, Carlos Gonzalez

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Transcendent Aspects of Proton Channels.Annual review of physiology · 2024
    Review
  8. Review
  9. Trapping Charge Mechanism in Hv1 Channels (International journal of molecular sciences · 2023
    Article
  10. Article
  11. Article
  12. Mechanosensitive aquaporins.Biophysical reviews · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Aquaporin Gating: A New Twist to Unravel Permeation through Water Channels.International journal of molecular sciences · 2022
    Review
  18. Expression of HProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emerson M CarmonaCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile.ORCID 0000-0003-1332-0372
Miguel FernandezCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile.
Juan J Alvear-AriasCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile.ORCID 0000-0003-2536-8568
Alan NeelyCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile.ORCID 0000-0002-6007-2159
H Peter LarssonDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL 33136.ORCID 0000-0002-1688-2525
Osvaldo AlvarezCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile.ORCID 0000-0001-8558-580X
Jose Antonio GarateCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile.ORCID 0000-0002-8345-968X
Ramon LatorreCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile.ORCID 0000-0002-6044-5795
Carlos GonzalezCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, 2351319 Valparaíso, Chile; carlos.gonzalezl@uv.cl.

Funding

Molecular mechanisms of voltage-gated proton channelsR01HL095920 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LARSSON, HANS PETER · 2010 to 2013
$1.5M
NHLBI NIH HHS R01 HL095920
6 · The paper itself

Abstract

The dissipation of acute acid loads by the voltage-gated proton channel (H

Indexed as

AlgorithmsModels, BiologicalProtonsAmino Acid SequenceAnimalsFemaleHumansHydrogen-Ion ConcentrationIon Channel GatingIon ChannelsMembrane PotentialsMiceMolecular Dynamics SimulationMutationOocytesSequence Homology, Amino AcidIon ChannelsProtonscouplinggating currentsHv1pH dependencevoltage sensor

Identifiers

PMID33941706
PMCPMC8126849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.