Evidence map›Paper›PMID 33941636›Full record

ArticleBMJ open2021

Air Pollution, housing and respirfatory tract Infections in Children: NatIonal birth Cohort study (PICNIC): study protocol.

Graziella Favarato, Tom Clemens, Steven Cunningham, Chris Dibben, Alison Macfarlane, Ai Milojevic, Jonathon Taylor, Linda Petronella Martina Maria Wijlaars, Rachael Wood, Pia Hardelid

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Graziella FavaratoPopulation, Policy and Practice Research and Teaching Department, University College London Institute of Child Health, London, UK.
Tom ClemensSchool of Geosciences, The University of Edinburgh, Edinburgh, UK.
Steven CunninghamCentre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
Chris DibbenSchool of Geosciences, The University of Edinburgh, Edinburgh, UK.
Alison MacfarlaneDepartment of Midwifery, City University, London, UK.
Ai MilojevicDepartment of Social and Environmental Health Research, London School of Hygiene & Tropical Medicine, London, UK.
Jonathon TaylorFaculty of Built Environment, Tampere University, Tampere, Finland.
Linda Petronella Martina Maria WijlaarsPopulation, Policy and Practice Research and Teaching Department, University College London Institute of Child Health, London, UK.ORCID 0000-0003-1222-2922
Rachael WoodClinical and Public Health Intelligence Team, Public Health Scotland, Edinburgh, UK.ORCID 0000-0003-4453-623X
Pia HardelidPopulation, Policy and Practice Research and Teaching Department, University College London Institute of Child Health, London, UK p.hardelid@ucl.ac.uk.ORCID 0000-0002-0154-1306
University College London · GBUniversity of Edinburgh · GBCentre for Inflammation Research · GBCity, University of London · GBLondon School of Hygiene & Tropical Medicine · GBPublic Health Scotland · GBTampere University · FI

Funding

Medical Research Council MR/T016558/1
6 · The paper itself

Abstract

introductionRespiratory tract infections (RTIs) are the most common reason for hospital admission among children <5 years in the UK. The relative contribution of ambient air pollution exposure and adverse housing conditions to RTI admissions in young children is unclear and has not been assessed in a UK context. METHODS AND ANALYSIS: The aim of the PICNIC study (Air Pollution, housing and respiratory tract Infections in Children: NatIonal birth Cohort Study) is to quantify the extent to which in-utero, infant and childhood exposures to ambient air pollution and adverse housing conditions are associated with risk of RTI admissions in children <5 years old. We will use national administrative data birth cohorts, including data from all children born in England in 2005-2014 and in Scotland in 1997-2020, created via linkage between civil registration, maternity and hospital admission data sets. We will further enhance these cohorts via linkage to census data on housing conditions and socioeconomic position and small area-level data on ambient air pollution and building characteristics. We will use time-to-event analyses to examine the association between air pollution, housing characteristics and the risk of RTI admissions in children, calculate population attributable fractions for ambient air pollution and housing characteristics, and use causal mediation analyses to explore the mechanisms through which housing and air pollution influence the risk of infant RTI admission. ETHICS, EXPECTED IMPACT AND DISSEMINATION: To date, we have obtained approval from six ethics and information governance committees in England and two in Scotland. Our results will inform parents, national and local governments, the National Health Service and voluntary sector organisations of the relative contribution of adverse housing conditions and air pollution to RTI admissions in young children. We will publish our results in open-access journals and present our results to the public via parent groups and social media and on the PICNIC website. Code and metadata will be published on GitHub.

Indexed as

Air PollutantsAir PollutionChildChild, PreschoolCohort StudiesEnglandFemaleHousingHumansInfantPregnancyScotlandState MedicineAir Pollutantsepidemiologypaediatricspublic healthrespiratory infections

Identifiers

PMID33941636
PMCPMC8098990
OpenAlexW3158977336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.