Evidence map›Paper›PMID 33941620›Full record

ArticleMolecular and cellular biology2021

Autism-Associated Vigilin Depletion Impairs DNA Damage Repair.

Shahid Banday, Raj K Pandita, Arjamand Mushtaq, Albino Bacolla, Ulfat Syed Mir, Dharmendra Kumar Singh, Sadaf Jan, Krishna P Bhat, Clayton R Hunt, Ganesh Rao and 4 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Exploring key genes and pathways associated with sex differences in autism spectrum disorder: integrated bioinformatic analysis.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  8. Identification of Male Sex-Related Genes Regulated byInternational journal of molecular sciences · 2023
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Shahid Banday *Chromatin and Epigenetics Lab, Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Raj K Pandita *Houston Methodist Research Institute, Houston, Texas, USA.
Arjamand Mushtaq *Chromatin and Epigenetics Lab, Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Albino BacollaDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Ulfat Syed MirChromatin and Epigenetics Lab, Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Dharmendra Kumar SinghHouston Methodist Research Institute, Houston, Texas, USA.
Sadaf JanChromatin and Epigenetics Lab, Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Krishna P BhatDepartment of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Clayton R HuntHouston Methodist Research Institute, Houston, Texas, USA.
Ganesh RaoBaylor College of Medicine, Houston, Texas, USA.
Vijay K CharakaHouston Methodist Research Institute, Houston, Texas, USA.
John A TainerDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Tej K PanditaHouston Methodist Research Institute, Houston, Texas, USA.
Mohammad AltafChromatin and Epigenetics Lab, Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Houston Methodist · USUniversity of Kashmir · INThe University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · US

Funding

Transcription-Coupled & Replication-Associated Excision RepairP01CA092584 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI WALTER J. CHAZIN · 2001 to 2026
$89.6M
Mesoscale and Nanoscale Technologies Integrated by Structures for DNA Repair Complexes (MANTIS-DRC)R35CA220430 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI John A. Tainer · 2018 to 2026
$7.6M
CHROMATIN MODIFYING FACTORS CONTROL RADIATION RESPONSE AND GENOMIC STABILITYR01CA129537 · NCI · WASHINGTON UNIVERSITY · PI PANDITA, TEJ K · 2008 to 2018
$3.3M
Role of Heterochromatin protein 1 Beta in Genome Maintenance and OncogenesisR01GM109768 · NIGMS · METHODIST HOSPITAL RESEARCH INSTITUTE · PI PANDITA, TEJ K · 2014 to 2017
$1.2M
NCI NIH HHS P01 CA092584NCI NIH HHS R01 CA129537NCI NIH HHS R35 CA220430NIGMS NIH HHS R01 GM109768
6 · The paper itself

Abstract

Vigilin (Vgl1) is essential for heterochromatin formation, chromosome segregation, and mRNA stability and is associated with autism spectrum disorders and cancer: vigilin, for example, can suppress proto-oncogene c-

Indexed as

DNA Breaks, Double-StrandedAutistic DisorderBRCA1 ProteinDNA RepairDNA ReplicationGenomic InstabilityHumansProto-Oncogene MasRad51 RecombinaseRNA-Binding ProteinsBRCA1 ProteinBRCA1 protein, humanMAS1 protein, humanProto-Oncogene MasRad51 RecombinaseRNA-Binding Proteinsautism-related disorderscancerDNA repairhistone acetylationhomologous recombinationRad51replicative stressvigilin

Identifiers

PMID33941620
PMCPMC8224237
OpenAlexW3158159413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.