Evidence map›Paper›PMID 33941579›Full record

ArticleInfection and immunity2021

A Dynamic, Ring-Forming Bactofilin Critical for Maintaining Cell Size in the Obligate Intracellular Bacterium Chlamydia trachomatis.

Mary R Brockett, Junghoon Lee, John V Cox, George W Liechti, Scot P Ouellette

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Halofilins as emerging bactofilin families of archaeal cell shape plasticity orchestrators.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Distinct regions ofeLife · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mary R Brockett *Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA.
Junghoon Lee *Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
John V CoxDepartment of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
George W LiechtiDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA.
Scot P OuelletteDepartment of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Uniformed Services University of the Health Sciences · USUniversity of Nebraska Medical Center · USUniversity of Tennessee Health Science Center · US

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL L SORGEN · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0M
Research Pilot Project ProgramP30GM106397 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2013 to 2017
$4.9M
Cellular organization, division, and differentiation in an ancient, genetically reduced bacteriumR35GM138202 · NIGMS · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI GEORGE WARREN LIECHTI · 2020 to 2026
$2.0M
Polarized Chlamydial Cell Division in the Absence of FtsZR35GM124798 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OUELLETTE, SCOT P · 2017 to 2021
$1.8M
NCI NIH HHS P30 CA036727NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P30 GM106397NIGMS NIH HHS R35 GM124798NIGMS NIH HHS R35 GM138202
6 · The paper itself

Abstract

Bactofilins are polymer-forming cytoskeletal proteins that are widely conserved in bacteria. Members of this protein family have diverse functional roles such as orienting subcellular molecular processes, establishing cell polarity, and aiding in cell shape maintenance. Using sequence alignment to the conserved bactofilin domain, we identified a bactofilin ortholog, BacA

Indexed as

Host-Pathogen InteractionsBacterial ProteinsCell DivisionChlamydia InfectionsChlamydia trachomatisCytoskeletal ProteinsGene Expression Regulation, BacterialHumansPeptidoglycanBacterial ProteinsCytoskeletal ProteinsPeptidoglycanbactofilincell divisioncell morphologycell polarityChlamydia

Identifiers

PMID33941579
PMCPMC8281209
OpenAlexW3159307756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.