Observational studyBrazilian journal of anesthesiology (Elsevier)
Association of postpartum depression and epidural analgesia in women during labor: an observational study.
Observational study in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Effects of transversus abdominis and erector spinae plane blocks on postoperative pain control and postpartum depression after cesarean section: a randomized prospective study.Turkish journal of medical sciences · 2026Trial
- Association between the effectiveness of labor epidural analgesia and postpartum depression: a prospective cohort study.Journal of anesthesia · 2026Observational
- Labor Epidural Anesthesia and Postpartum Depression Risk: Prospective Observation Study and Mendelian Randomization Analysis.Drug design, development and therapy · 2025Observational
- Association of inpatient postpartum recovery with patient-reported outcome measures following hospital discharge: a prospective cohort study.BMC pregnancy and childbirth · 2024Observational
- Depressive Symptoms during Pregnancy and the Postpartum Period: A Tertiary Hospital Experience.Medicina (Kaunas, Lithuania) · 2024Article
- Article
- Association between epidural analgesia and postpartum psychiatric disorders: A meta-analysis.Heliyon · 2024Article
- Association between the use of epidural analgesia during labour and incidence of postpartum depression.PloS one · 2023Observational
- Association of General Anesthesia and Neuraxial Anesthesia in Caesarean Section with Maternal Postpartum Depression: A Retrospective Nationwide Population-Based Cohort Study.Journal of personalized medicine · 2022Article
- Challenges in obstetric anesthesia.Brazilian journal of anesthesiology (Elsevier)Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesPostpartum depression affects women, manifesting with depressed mood, insomnia, psychomotor retardation, and suicidal thoughts. Our study examined if there is an association between epidural analgesia use and postpartum depression.
methodsPatients were divided into two groups. One group received epidural analgesia during labor while the second group did not. The Edinburgh postnatal depression scale (EPDS) was administered to patients prior to birth and 6 weeks postpartum. Pain severity was assessed by the Visual Analogue Scale (VAS) during labor and at 24hours postpartum.
resultsOf the 92 patients analyzed, 47.8% (n=44) received epidural analgesia. We detected significantly higher VAS score during labor (p= 0.007) and 24 hours postpartum (p = 0.0001) in the group without epidural analgesia. At 6 weeks postpartum, a significant difference was observed between the EPDS scores of both groups (p= 0.0001). Regression analysis revealed higher depression scores in patients experiencing higher levels of pain during labor (OR = 0.572, p= 0.039). Epidural analgesia strongly correlated with lower scores of depression (OR = 0.29, p= 0.0001).
conclusionThe group that received epidural analgesia had lower pain scores. A high correlation between epidural analgesia and lower depression levels was found. Pregnant women giving birth via the vaginal route and having high pain scores could reduce postnatal depression scores using epidural labor analgesia. Pregnant women should opt for epidural analgesia during labor to lessen postpartum depression levels.
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