Evidence map›Paper›PMID 33941206›Full record

ReviewJournal of nanobiotechnology2021

Construction of nanomaterials as contrast agents or probes for glioma imaging.

Wei Zhao, Xiangrong Yu, Shaojun Peng, Yu Luo, Jingchao Li, Ligong Lu

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Innovative applications of advanced nanomaterials in cerebrovascular imaging.Frontiers in bioengineering and biotechnology · 2024
    Review
  10. Review
  11. Visualization of ferroptosis in brain diseases and ferroptosis-inducing nanomedicine for glioma.American journal of nuclear medicine and molecular imaging · 2023
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei ZhaoZhuhai Precision Medical Center, Zhuhai Interventional Medical Center, Zhuhai People's Hospital (Affiliated With Jinan University), Zhuhai, 519000, Guangdong, China.
Xiangrong YuZhuhai Precision Medical Center, Zhuhai Interventional Medical Center, Zhuhai People's Hospital (Affiliated With Jinan University), Zhuhai, 519000, Guangdong, China.
Shaojun PengZhuhai Precision Medical Center, Zhuhai Interventional Medical Center, Zhuhai People's Hospital (Affiliated With Jinan University), Zhuhai, 519000, Guangdong, China.
Yu LuoSchool of Chemical Science and Engineering, Tongji University, 1239 Siping Road, Shanghai, China. yuluo@tongji.edu.cn.
Jingchao LiCollege of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620, China. jcli@dhu.edu.cn.ORCID http://orcid.org/0000-0002-8994-3202
Ligong LuZhuhai Precision Medical Center, Zhuhai Interventional Medical Center, Zhuhai People's Hospital (Affiliated With Jinan University), Zhuhai, 519000, Guangdong, China. luligong1969@126.com.

Funding

China Postdoctoral Science Foundation 2019M663361National Key Research and Development Program of China 2017YFA0205200National Natural Science Foundation of China 81701684National Natural Science Foundation of China 81903165the Opening Project of State Key Laboratory of High-Performance Ceramics and Superfine Microstructure SKL201908SIC
6 · The paper itself

Abstract

Malignant glioma remains incurable largely due to the aggressive and infiltrative nature, as well as the existence of blood-brain-barrier (BBB). Precise diagnosis of glioma, which aims to accurately delineate the tumor boundary for guiding surgical resection and provide reliable feedback of the therapeutic outcomes, is the critical step for successful treatment. Numerous imaging modalities have been developed for the efficient diagnosis of tumors from structural or functional aspects. However, the presence of BBB largely hampers the entrance of contrast agents (Cas) or probes into the brain, rendering the imaging performance highly compromised. The development of nanomaterials provides promising strategies for constructing nano-sized Cas or probes for accurate imaging of glioma owing to the BBB crossing ability and other unique advantages of nanomaterials, such as high loading capacity and stimuli-responsive properties. In this review, the recent progress of nanomaterials applied in single modal imaging modality and multimodal imaging for a comprehensive diagnosis is thoroughly summarized. Finally, the prospects and challenges are offered with the hope for its better development.

Indexed as

Contrast MediaNanostructuresAnimalsBlood-Brain BarrierBrain NeoplasmsCone-Beam Computed TomographyDiagnostic ImagingGliomaMagnetic Resonance ImagingOptical ImagingContrast MediaBiomedical imagingBlood–brain-barrierContrast agentsGlioma imagingNanomaterialsProbes

Identifiers

PMID33941206
PMCPMC8091158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.