Evidence map›Paper›PMID 33941035›Full record

ArticleScandinavian journal of gastroenterology2021

LINGO3 regulates mucosal tissue regeneration and promotes TFF2 dependent recovery from colitis.

Kelly M Zullo, Bonnie Douglas, Nicole M Maloney, Yingbiao Ji, Yun Wei, Karl Herbine, Rachel Cohen, Christopher Pastore, Zvi Cramer, Xin Wang and 7 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scandinavian journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. EnterotoxigenicTransboundary and emerging diseases · 2025
    Article
  5. Trefoil Factor Family: A Troika for Lung Repair and Regeneration.American journal of respiratory cell and molecular biology · 2022
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Kelly M ZulloDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Bonnie DouglasDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Nicole M MaloneyDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Yingbiao JiDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Yun WeiDepartment of Medicine, Division of Experimental Medicine, University of California, San Francisco, CA, USA.
Karl HerbineDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Rachel CohenDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Christopher PastoreDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Zvi CramerDepartment of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Xin WangDepartment of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Wenjie WeiDepartment of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Ma SomsoukDepartment of Pathology, University of California, San Francisco, CA, USA.
Li Yin HungDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Christopher LengnerDepartment of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
Michael H KohanskiDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA.
Noam A CohenDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA.
De'Broski R HerbertDepartment of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
University of Pennsylvania · USUniversity of California, San Francisco · USMonell Chemical Senses Center · USPhiladelphia VA Medical Center · US

Funding

Trefoil factor proteins regulate inflammation and immunityU01AI125940 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 2016 to 2021
$2.8M
Alternative Macrophage Activation Limits ImmunopathologyR01GM083204 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 2007 to 2018
$2.5M
Trefoil Factors Regulate Th2 ImmunityR01AI095289 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 2011 to 2015
$2.1M
Using transgenic parasitic nematodes to investigate Type 2 immunityR21AI144572 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R, LOK, JAMES B · 2019 to 2020
$443k
NIAID NIH HHS R01 AI095289NIAID NIH HHS R21 AI144572NIAID NIH HHS U01 AI125940NIGMS NIH HHS R01 GM083204
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ColitisIntestinal MucosaHumansOrganoidsTrefoil Factor-2Wound HealingTFF2 protein, humanTrefoil Factor-2DSS colitisintestinal stem cellsLINGO3Lrg5mucosal barriersTFF2

Identifiers

PMID33941035
PMCPMC8647134
OpenAlexW3158242906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.