ArticleWorld neurosurgery2021
Subarachnoid Hemorrhage and COVID-19: An Analysis of 282,718 Patients.
Article in World neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of COVID-19 on clinical outcomes in people undergoing neurosurgery: a systematic review and meta-analysis.Systematic reviews · 2023Pooled it
- Characteristics of subarachnoid hemorrhage associated with COVID-19 infection: A systematic review and descriptive analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023Pooled it
- Clinical outcomes of neurosurgical patients during the COVID-19 pandemic: a systematic review and meta-analysis of global data.Acta neurologica Belgica · 2026Review
- Characterizing Infiltrating Macrophages in Intracranial Aneurysm with IA Animal Models and Spatial Transcriptomics.Translational stroke research · 2026Review
- Clinical characteristics and outcomes of SARS-CoV-2-associated stroke: a large multicenter national cohort study.Einstein (Sao Paulo, Brazil) · 2026Article
- Two Cases of Subarachnoid Hemorrhage Associated With COVID-19 Infection Yielding Favorable Functional Outcomes.Cureus · 2025Article
- Predicting Mortality in Subarachnoid Hemorrhage Patients Using Big Data and Machine Learning: A Nationwide Study in Türkiye.Journal of clinical medicine · 2025Article
- Persistent intracranial hyper-inflammation in ruptured cerebral aneurysm after COVID-19: case report and review of the literature.BMC neurology · 2024Review
- Article
- The Impact of SARS-CoV-2 Infection on the Length of Stay in the Neuro-ICU:A Prospective Multicenter Cohort Study in Eight Neuro-ICU, China Between February and April 2023.Neuropsychiatric disease and treatment · 2024Article
- Cerebrovascular Manifestations of SARS-CoV-2: A Comprehensive Review.Current treatment options in neurology · 2023Review
- Pandemic impact on aneurysmal subarachnoid hemorrhage in Peru's high COVID-19 lethality setting: A public institutional experience.Surgical neurology international · 2023Article
- A Non-traumatic Non-aneurysmal Subarachnoid Hemorrhage in a Mild COVID-19 Infection: A Case Report.Cureus · 2023Article
- Vertebral artery dissecting aneurysm rupture under severe COVID-19.Brain hemorrhages · 2022Article
- Acute Neurologic Complications of COVID-19 and Postacute Sequelae of COVID-19.Critical care clinics · 2022Review
- Severe stroke in patients admitted to intensive care unit after COVID-19 infection: Pictorial essay of a case series.Brain hemorrhages · 2022Article
- Utilization and Outcomes of Acute Revascularization Treatments in Ischemic Stroke Patients with SARS-CoV-2 Infection.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Article
- Aneurismal subarachnoid hemorrhage during the COVID-19 outbreak in a Hub and Spoke system: observational multicenter cohort study in Lombardy, Italy.Acta neurochirurgica · 2022Observational
- Frequency of Neurological Diseases After COVID-19, Influenza A/B and Bacterial Pneumonia.Frontiers in neurology · 2022Article
- The relationship between COVID-19 infection and intracranial hemorrhage: A systematic review.Brain hemorrhages · 2021Review
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Authors and funding
12 authors.
Funding
Abstract
backgroundIntracranial hemorrhage (including subarachnoid hemorrhage [SAH]) has been reported in 0.3%-1.2% of patients with coronavirus disease 2019 (COVID-19). However, no study has evaluated the risk of SAH in patients with COVID-19.
methodsWe analyzed data from 62 health care facilities using the Cerner de-identified COVID-19 dataset.
resultsThere were 86 (0.1%) and 376 (0.2%) patients with SAH among 85,645 patients with COVID-19 and 197,073 patients without COVID-19, respectively. In the multivariate model, there was a lower risk of SAH in patients with COVID-19 (odds ratio 0.5, 95% confidence interval 0.4-0.7, P < 0.0001) after adjusting for sex, age strata, race/ethnicity, hypertension, and nicotine dependence/tobacco use. The proportions of patients who developed pneumonia (58.1% vs. 21.3%, P < 0.0001), acute kidney injury (43% vs. 27.7%, P = 0.0005), septic shock (44.2% vs. 20.7%, P < 0.0001), and respiratory failure (64.0% vs. 39.1%, P < 0.0001) were significantly higher among patients with SAH and COVID-19 compared with patients without COVID-19. The in-hospital mortality among patients with SAH and COVID-19 was significantly higher compared with patients without COVID-19 (31.4% vs. 12.2%, P < 0.0001).
conclusionsThe risk of SAH was not increased in patients with COVID-19. The higher mortality in patients with SAH and COVID-19 compared with patients without COVID-19 is likely mediated by higher frequency of systemic comorbidities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.