Evidence map›Paper›PMID 33940207›Full record

ArticleAcademic pediatrics2021

Adverse Childhood Experiences and Association With Pediatric Asthma Severity in the 2016-2017 National Survey of Children's Health.

Mindy K Ross, Tahmineh Romero, Peter G Szilagyi

Abstract read
In one paragraph

Article in Academic pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mindy K RossUniversity of California Los Angeles, Department of Pediatrics, Pediatric Pulmonology and Sleep Medicine (MK Ross), Los Angeles, Calif. Electronic address: mross@mednet.ucla.edu.
Tahmineh RomeroUniversity of California Los Angeles, Department of Medicine, Statistical Core (T Romero), Los Angeles, Calif.
Peter G SzilagyiUniversity of California Los Angeles, Department of Pediatrics, General Pediatrics (PG Szilagyi), Los Angeles, Calif.

Funding

Patient Entered Data for Clinical Decision Support to Personalize Pediatric Asthma ManagementK23HL148502 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROSS, MINDY K · 2020 to 2024
$980k
NHLBI NIH HHS K23 HL148502
6 · The paper itself

Abstract

objectivesPrior studies have found that adverse childhood experiences (ACEs) are associated with asthma prevalence and onset, presumably related to stress and increased inflammation. We hypothesized that ACEs may be associated with asthma severity as well. We studied the 2016-2017 US National Survey of Children's Health dataset to explore the relationship between ACEs and pediatric asthma severity.

methodsWe analyzed children ages 0 to 17 years old who had current caregiver-reported asthma diagnosed by a healthcare provider. We reported descriptive characteristics using chi-square analysis of variance (ANOVA) and used multivariable regression analysis to assess the relationship of cumulative and individual ACEs with asthma severity. Survey sampling weights and SAS survey procedures were implemented to produce nationally representative results.

resultsOur analysis included 3691 children, representing a population of 5,465,926. Unadjusted analysis demonstrated that ACEs - particularly household economic hardship, parent/guardian served time in jail, witnessed household violence, or victim/witness of neighborhood violence - were each associated with higher odds of moderate/severe caregiver-reported asthma. After controlling for confounders possibly associated with both exposure (ACEs) and outcome (asthma severity), children who witnessed parent/adult violence had higher adjusted odds of caregiver-reported moderate/severe asthma. (1.67, confidence interval 1.05-2.64, P = .03)

conclusionsIntrafamilial witnessed household violence is significantly associated with caregiver-reported moderate/severe asthma.

Indexed as

Adverse Childhood ExperiencesAsthmaAdolescentAdultChildChild HealthChild, PreschoolCross-Sectional StudiesHumansInfantInfant, NewbornPovertyadverse childhood experiencesasthmapediatrics

Identifiers

PMID33940207
PMCPMC8947844

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.