Evidence map›Paper›PMID 33939937›Full record

ArticleSubstance use & misuse2021

"The Doctor Says You Cannot Have [Buprenorphine]" Autonomy and Use of Prescribed or Non-Prescribed Buprenorphine.

Benjamin T Hayes, Andrea Jakubowski, Christine Fitzsimmons, Billy Garcia, Franklin Ramirez, Aaron D Fox

Open access · greenAbstract read
In one paragraph

Article in Substance use & misuse, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Benjamin T HayesDivision44 of General Internal Medicine, Montefiore Medical Center, Bronx, NY, USA.ORCID 0000-0002-4282-6869
Andrea JakubowskiDivision44 of General Internal Medicine, Montefiore Medical Center, Bronx, NY, USA.ORCID 0000-0001-5651-5589
Christine FitzsimmonsNew York Harm Reduction Educators, New York, NY, USA.
Billy GarciaWashington Heights Corner Project, New York, NY, USA.
Franklin RamirezNew York Harm Reduction Educators, New York, NY, USA.
Aaron D FoxDivision44 of General Internal Medicine, Montefiore Medical Center, Bronx, NY, USA.ORCID 0000-0002-6904-4795
Montefiore Medical Center · USHarm Reduction Services · USNeighborhood House · US

Funding

Impact of PTSD and trauma reexposure on buprenorphine maintenance treatment in syringe exchange programsR01DA044878 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FOX, AARON D · 2017 to 2022
$3.7M
NIDA NIH HHS R01 DA044878
6 · The paper itself

Abstract

backgroundPeople may overcome barriers to professional buprenorphine treatment by using non-prescribed buprenorphine (NPB) to manage opioid use disorder (OUD). Little is known about how people perceive NPB differently than formal treatment. This qualitative study investigated how and why people use NPB as an alternative to formal treatment.

methodsIn-depth, semi-structured interviews were conducted with participants of harm reduction agencies (

resultsThree main factors drove decisions about prescribed and non-prescribed buprenorphine use: 1) autonomy; 2) treatment goals; and 3) negative early experiences with NPB. An overarching theme from our analysis was that participants valued autonomy in seeking to control their substance use. NPB was a valuable tool toward this goal and professional OUD treatment could impede autonomy. Participants mostly used NPB to "self-manage" OUD symptoms. Many participants had concerns about long-term buprenorphine treatment and instead used NPB over short periods of time. Several participants also reported negative experiences with NPB, including symptoms of withdrawal, which then deterred them from seeking out professional treatment.

conclusionsThese results support prior studies showing that people use NPB to self-manage withdrawal symptoms and to reduce use of illicit opioids. Despite these benefits, participants focused on short-term goals and negative consequences were common. Increasing buprenorphine treatment engagement may require attention to patients' sense of autonomy, and also assurance that long-term treatment is safe, effective, and reliably accessible.

Indexed as

BuprenorphineOpioid-Related DisordersAnalgesics, OpioidHumansMotivationOpiate Substitution TreatmentAnalgesics, OpioidBuprenorphineautonomyBuprenorphineharm reductionnon-prescribed buprenorphineopioid use disorderqualitative

Identifiers

PMID33939937
PMCPMC8754088
OpenAlexW3158305748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.