Evidence map›Paper›PMID 33939336›Full record

ReviewCancer reports (Hoboken, N.J.)2021

Recommendations for streamlining precision medicine in breast cancer care in Latin America.

Isabel Alvarado-Cabrero, Franco Doimi, Virginia Ortega, Jurema Telles de Oliveira Lima, Rubén Torres, Lilian Torregrosa

Open access · goldAbstract readReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Isabel Alvarado-CabreroDepartment of Pathology, Mexican Oncology Hospital, IMSS, Mexico, Mexico.ORCID 0000-0003-4000-9280
Franco DoimiDepartment of Pathology, Oncosalud AUNA, Lima, Peru.
Virginia OrtegaDepartment of Pathology, Diagnostico SRL, Montevideo, Uruguay.
Jurema Telles de Oliveira LimaDepartment of Pathology, IMIP, Recife, Brazil.
Rubén TorresRector de la Universidad ISALUD, R.Argentina.
Lilian TorregrosaDepartment of Breast and Soft Tissue Surgery, Pontificia Universidad Javeriana, Bogotá, Colombia.
EsSALUD · PEInstituto de Medicina Integral Professor Fernando Figueira · BRMexican Social Security Institute · MXPontificia Universidad Javeriana · COUniversidad Isalud · AR

Funding

Health Foundation
6 · The paper itself

Abstract

backgroundThe incidence of breast cancer (BC) in LMICs has increased by more than 20% within the last decade. In areas such as Latin America (LA), addressing BC at national levels evoke discussions surrounding fragmented care, limited resources, and regulatory barriers. Precision Medicine (PM), specifically companion diagnostics (CDx), links disease diagnosis and treatment for better patient outcomes. Thus, its application may aid in overcoming these barriers. RECENT

findingsA panel of LA experts in fields related to BC and PM were provided with a series of relevant questions to address prior to a multi-day conference. Within this conference, each narrative was edited by the entire group, through numerous rounds of discussion until a consensus was achieved. The panel proposes specific, realistic recommendations for implementing CDx in BC in LA and other LMIC regions. In these recommendations, the authors strived to address all barriers to the widespread use and access mentioned previously within this manuscript.

conclusionThis manuscript provides a review of the current state of CDx for BC in LA. Of most importance, the panel proposes practical and actionable recommendations for the implementation of CDx throughout the Region in order to identify the right patient at the right time for the right treatment.

Indexed as

Precision MedicineBiomarkers, TumorBreast NeoplasmsFemaleGenetic TestingHumansLatin AmericaPractice Guidelines as TopicBiomarkers, Tumorbreast cancerCDxcompanion diagnosticsLatin Americaprecision medicine

Identifiers

PMID33939336
PMCPMC8714537
OpenAlexW3159127233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.