Evidence map›Paper›PMID 33939241›Full record

ArticleCancer science2021

PP1 regulatory subunit NIPP1 regulates transcription of E2F1 target genes following DNA damage.

Shunsuke Hanaki, Makoto Habara, Takahiro Masaki, Keisuke Maeda, Yuki Sato, Makoto Nakanishi, Midori Shimada

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Sut-6/NIPP1 modulates tau toxicity.Human molecular genetics · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shunsuke HanakiDepartment of Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.ORCID https://orcid.org/0000-0002-7803-0547
Makoto HabaraDepartment of Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.ORCID https://orcid.org/0000-0001-6418-1291
Takahiro MasakiDepartment of Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.ORCID https://orcid.org/0000-0002-2948-0277
Keisuke MaedaDepartment of Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.ORCID https://orcid.org/0000-0002-5278-4500
Yuki SatoDepartment of Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.ORCID https://orcid.org/0000-0002-4137-6042
Makoto NakanishiDivision of Cancer Biology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6707-3584
Midori ShimadaDepartment of Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.ORCID https://orcid.org/0000-0002-2718-8600
Yamaguchi University · JPThe University of Tokyo · JP

Funding

Japanese Society for the Promotion of Science 18H02681MSD Life Science Foundation, Public Interest Incorporated Foundation
6 · The paper itself

Abstract

DNA damage induces transcriptional repression of E2F1 target genes and a reduction in histone H3-Thr

Indexed as

DNA DamageCell ProliferationCells, CulturedCheckpoint Kinase 1CRISPR-Cas SystemsCyclic AMP-Dependent Protein KinasesE2F1 Transcription FactorEndoribonucleasesEpigenetic RepressionGene Expression RegulationHistonesHumansPhosphoprotein PhosphatasesPhosphorylationPromoter Regions, GeneticProtein Phosphatase 1Checkpoint Kinase 1CHEK1 protein, humanCyclic AMP-Dependent Protein KinasesE2F1 protein, humanE2F1 Transcription FactorEndoribonucleasesHistonesneuropeptide Y4 receptorPhosphoprotein PhosphatasesPPP1R8 protein, humanProtein Phosphatase 1Receptors, Neuropeptide YRNA-Binding ProteinsRNA, MessengerDNA damageE2F1histone phosphorylationprotein phosphatasetranscription

Identifiers

PMID33939241
PMCPMC8253265
OpenAlexW3158574427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.